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Aptamer biosensor design for the detection of endocrine-disrupting chemicals small organic molecules using novel bioinformatics methods
Endocrine-disrupting chemicals (EDCs) are substances that can disrupt the normal
functioning of hormones. Using aptamers, which are biological recognition elements …
functioning of hormones. Using aptamers, which are biological recognition elements …
Structural dynamics and allostery of Rab proteins: strategies for drug discovery and design
Rab proteins represent the largest family of the Rab superfamily guanosine triphosphatase
(GTPase). Aberrant human Rab proteins are associated with multiple diseases, including …
(GTPase). Aberrant human Rab proteins are associated with multiple diseases, including …
Effects of nucleotide and end-dependent actin conformations on polymerization
L Jepsen, D Sept - Biophysical Journal, 2020 - cell.com
The regulation of actin is key for controlled cellular function. Filaments are regulated by actin-
binding proteins, but the nucleotide state of actin is also an important factor. From extended …
binding proteins, but the nucleotide state of actin is also an important factor. From extended …