Host defence peptides (HDPs) are short, cationic amphipathic peptides with diverse
sequences that are produced by various cells and tissues in all complex life forms. HDPs …

Although first studied for their antimicrobial activity, host defense peptides (HDPs) are now
widely recognized for their multifunctional roles in both the innate and adaptive immune …

Cathelicidins are host defense peptides with antimicrobial and immunomodulatory functions.
These effector molecules of the innate immune system of many vertebrates are diverse in …

Cationic host defense (antimicrobial) peptides were originally studied for their direct
antimicrobial activities. They have since been found to exhibit multifaceted …

The human cathelicidin hCAP18/LL-37 has become a paradigm for the pleiotropic roles of
peptides in host defence. It has a remarkably wide functional repertoire that includes direct …

Vitamin D signaling plays an essential role in innate defense against intracellular
microorganisms via the generation of the antimicrobial protein cathelicidin. In addition to …

Cathelicidins are short cationic peptides that are part of the innate immune system. At first,
these peptides were studied mostly for their direct antimicrobial killing capacity, but …

Autoreactive B and T cells are present in healthy, autoimmunity-free individuals, but they are
kept in check by various regulatory mechanisms. In systemic lupus erythematosus (SLE) …

LL‐37, also called cathelicidin, is an important part of the human immune system, which can
resist various pathogens. A plethora of experiments have demonstrated that it has the …

LL-37 is a C-terminal peptide proteolytically released from 18 kDa human cathelicidin
protein (hCAP18). Chronic infections, inflammation, tissue injury and tissue regeneration are …