The ability to select short DNA oligonucleotide sequences capable of binding solely to their
intended target is of great importance in develo** nucleic acid based detection …

This review describes design principles which chemists have applied to the construction of
DNA analogues for use in the recognition of specific DNA and RNA sequences. The focus is …

A unified view of polymer, dumbbell, and oligonucleotide nearest-neighbor (NN)
thermodynamics is presented. DNA NN ΔG° 37 parameters from seven laboratories are …

Two factors are mainly responsible for the stability of the DNA double helix: base pairing
between complementary strands and stacking between adjacent bases. By studying DNA …

Thermodynamic data were determined from UV absorbance vs temperature profiles of 23
oligonucleotides. These data were combined with data from the literature for 21 sequences …

Thermodynamic measurements are reported for 51 DNA duplexes with A⊙ A, C⊙ C, G⊙ G,
and T⊙ T single mismatches in all possible Watson− Crick contexts. These measurements …

Melting temperatures, T m, were systematically studied for a set of 92 DNA duplex oligomers
in a variety of sodium ion concentrations ranging from 69 mM to 1.02 M. The relationship …

Thermodynamics of 23 oligonucleotides with internal single C· T mismatches were obtained
by measuring UV absorbance as a function of temperature. Results from these 23 duplexes …

Stability of duplex DNA with respect to separation of complementary strands is crucial for
DNA executing its major functions in the cell and it also plays a central role in major …

The DNA double helix structure is stabilized by base-pairing and base-stacking interactions.
However, a comprehensive understanding of dinucleotide base-stacking energetics is …