Chemokine receptors are members of the G protein-coupled receptor superfamily. These
receptors are intimately involved in cell movement, and thus play a critical role in several …

Genetic resistance to infectious diseases is likely to involve a complex array of immune-
response and other genes with variants that impose subtle but significant consequences on …

Case Study Research: Principles and Practices aims to provide a general understanding of
the case study method as well as specific tools for its successful implementation. These tools …

Vectors derived from human immunodeficiency virus (HIV) are highly efficient vehicles for in
vivo gene delivery. However, their biosafety is of major concern. Here we exploit the …

HIV-1 and related viruses require co-receptors, in addition to CD4, to infect target cells. The
chemokine receptor CCR-5 (ref. 1) was recently demonstrated to be a co-receptor for …

Mathematical models, which are based on a firm understanding of biological interactions,
can provide nonintuitive insights into the dynamics of host responses to infectious agents …

The chemokine receptor 5 (CKR5) protein serves as a secondary receptor on CD4+ T
lymphocytes for certain strains of human immunodeficiency virus-type 1 (HIV-1). The CKR5 …

Case Selection for Case‐Study Analysis: Qualitative and Quantitative Techniques | The Oxford
Handbook of Political Methodology | Oxford Academic Skip to Main Content Advertisement …

A selective advantage against infectious disease associated with increased heterozygosity
at the human major histocompatibility complex [human leukocyte antigen (HLA) class I and …

Virus-specific CD4+ T helper lymphocytes are critical to the maintenance of effective
immunity in a number of chronic viral infections, but are characteristically undetectable in …