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[HTML][HTML] Uncovering the cells and circuits of touch in normal and pathological settings
The sense of touch is fundamental as it provides vital, moment-to-moment information about
the nature of our physical environment. Primary sensory neurons provide the basis for this …
the nature of our physical environment. Primary sensory neurons provide the basis for this …
Identification of lipid heterogeneity and diversity in the develo** human brain
The lipidome is currently understudied but fundamental to life. Within the brain, little is
known about cell-type lipid heterogeneity, and even less is known about cell-to-cell lipid …
known about cell-type lipid heterogeneity, and even less is known about cell-to-cell lipid …
Single cell profiling using ionic liquid matrix-enhanced secondary ion mass spectrometry for neuronal cell type differentiation
A high-throughput single cell profiling method has been developed for matrix-enhanced-
secondary ion mass spectrometry (ME-SIMS) to investigate the lipid profiles of neuronal …
secondary ion mass spectrometry (ME-SIMS) to investigate the lipid profiles of neuronal …
Antagonism of TRPV4 channels partially reduces mechanotransduction in rat skeletal muscle afferents
A Fukazawa, A Hori, N Hotta… - The Journal of …, 2023 - Wiley Online Library
Mechanical distortion of working skeletal muscle induces sympathoexcitation via thin fibre
afferents, a reflex response known as the skeletal muscle mechanoreflex. However, to date …
afferents, a reflex response known as the skeletal muscle mechanoreflex. However, to date …
Direct label-free imaging of brain tissue using synchrotron light: a review of new spectroscopic tools for the modern neuroscientist
The incidence of brain disease and brain disorders is increasing on a global scale.
Unfortunately, development of new therapeutic strategies has not increased at the same …
Unfortunately, development of new therapeutic strategies has not increased at the same …
Nanomedicine-driven neuropathic pain relief in a rat model is associated with macrophage polarity and mast cell activation
We explored the immune neuropathology underlying multi-day relief from neuropathic pain
in a rat model initiated at the sciatic nerve, by using a nanoemulsion-based nanomedicine …
in a rat model initiated at the sciatic nerve, by using a nanoemulsion-based nanomedicine …
A novel multi-modal platform to image molecular and elemental alterations in ischemic stroke
Stroke is a major global health problem, with the prevalence and economic burden
predicted to increase due to aging populations in western society. Following stroke …
predicted to increase due to aging populations in western society. Following stroke …
Retinal oxidative stress at the onset of diabetes determined by synchrotron FTIR widefield imaging: towards diabetes pathogenesis
Diabetic retinopathy is a microvascular complication of diabetes that can lead to blindness.
In the present study, we aimed to determine the nature of diabetes-induced, highly localized …
In the present study, we aimed to determine the nature of diabetes-induced, highly localized …
Bioinspired scaffold induced regeneration of neural tissue
In the last decade, nerve tissue engineering has attracted much attention due to the
incapability of self-regeneration. Nerve tissue regeneration is mainly based on scaffold …
incapability of self-regeneration. Nerve tissue regeneration is mainly based on scaffold …
FTIR studies of the similarities between pathology induced protein aggregation in vivo and chemically induced protein aggregation ex vivo
Fourier transform infrared (FTIR) spectroscopy has been well documented to discriminate
between protein secondary structures, at the micron scale. This capability has enabled in …
between protein secondary structures, at the micron scale. This capability has enabled in …