Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …

This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Cancer has emerged over the last decades as one of the deadliest diseases in the world.
Among the most commonly used techniques (ie surgery, immunotherapy, radiotherapy or …

Photodynamic therapy (PDT), a therapeutic mode involving light triggering, has been
recognized as an attractive oncotherapy treatment. However, nonnegligible challenges …

Transition metal complexes are of increasing interest as photosensitizers in photodynamic
therapy (PDT) and, more recently, for photochemotherapy (PCT). In recent years, Ru (II) …

Hypoxic tumours are a major problem for cancer photodynamic therapy. Here, we show that
photoredox catalysis can provide an oxygen-independent mechanism of action to combat …

Metal-based drugs and imaging agents are extensively used in the clinic for the treatment
and diagnosis of cancers and a wide range of other diseases. The current clinical arsenal of …

In this Minireview, we highlight recent advances in the design of transition metal complexes
for photodynamic therapy (PDT) and photoactivated chemotherapy (PACT), and discuss the …

Reactive oxygen species (ROS) play a crucial role in regulating the metabolism of tumor
growth, metastasis, death and other biological processes. ROS-based nanodynamic …

Cancer is rapidly becoming the top killer in the world. Most of the FDA approved anticancer
drugs are organic molecules, while metallodrugs are very scarce. The advent of the first …