Traditional treatments such as chemotherapy and surgery usually cause severe side effects
and excruciating pain. The emergence of nanomedicines and minimally invasive therapies …

Exosome application has emerged as a promising nanotechnology discipline for various
diseases therapeutics and diagnoses. Owing to the natural properties of efficient drug …

We designed a unique nanocapsule for efficient single CRISPR-Cas9 capsuling,
noninvasive brain delivery and tumor cell targeting, demonstrating an effective and safe …

Glioblastoma (GBM) is an intractable malignancy with high recurrence and mortality.
Combinatorial therapy based on temozolomide (TMZ) and cisplatin (CDDP) shows …

Malignant brain tumors, a heterogeneous group of primary and metastatic neoplasms in the
central nervous system (CNS), are notorious for their highly invasive and devastating …

Layered double hydroxides (LDHs), also known as anionic clays or hydrotalcite-like
compounds, are a class of nanomaterials that attained great attention as a carrier for drug …

Inspired by natural biology, cell membrane-mimetic surface engineering and cell membrane
camouflaging technology have been widely investigated. Notably, the cell membrane …

Nanosystems have shown encouraging outcomes and substantial progress in the areas of
drug delivery and biomedical applications. However, the controlled and targeted delivery of …

Nanoparticle‐based small interfering RNA (siRNA) therapy shows great promise for
glioblastoma (GBM). However, charge associated toxicity and limited blood–brain‐barrier …

Nanoparticles (NPs) represent an important advance for delivering diagnostic and
therapeutic agents across the blood–brain barrier. However, NP clearance is critical for …