Publisher Summary This chapter investigates the anatomy and taxonomy of protein
structures. A protein is a polypeptide chain made up of amino acid residues linked together …

General principles of protein structure, stability, and folding kinetics have recently been
explored in computer simulations of simple exact lattice models. These models represent …

We have developed an automatic algorithm STRIDE for protein secondary structure
assignment from atomic coordinates based on the combined use of hydrogen bond energy …

Using an empirical analysis of experimental data we have estimated a set of energy
contributions which accounts for the stability of isolated α-helices. With this database and an …

Helix‐cap** motifs are specific patterns of hydrogen bonding and hydrophobic
interactions found at or near the ends of helices in both proteins and peptides. In an α‐helix …

In light of the recent accumulated knowledge on SARS-CoV-2 and its mode of human cells
invasion, the binding of viral spike glycoprotein to human Angiotensin Converting Enzyme 2 …

Thirty single cysteine substitution mutants of T4 lysozyme have been prepared and spin-
labeled with a sulfhydryl-specific nitroxide reagent in order to systematically investigate the …

The solution structure of a human immunodeficiency virus type-1 (HIV-1) Rev peptide bound
to stem-loop IIB of the Rev response element (RRE) RNA was solved by nuclear magnetic …

The information about the conformational behavior of monomeric helical peptides in
solution, as well as the α-helix stability in proteins, has been previously utilized to derive a …

The de novo design of peptides and proteins has recently emerged as an approach for
investigating protein structure and function. Designed, helical peptides provide model …