Central neuropathic pain arises from a lesion or disease of the central somatosensory
nervous system such as brain injury, spinal cord injury, stroke, multiple sclerosis or related …

This review describes the progress that has been achieved since adaptive optics (AO) was
incorporated into the ophthalmoscope a quarter of a century ago, transforming our ability to …

Crossing the blood–brain barrier in primates is a major obstacle for gene delivery to the
brain. Adeno-associated viruses (AAVs) promise robust, non-invasive gene delivery from the …

With concurrent global epidemics of chronic pain and opioid use disorders, there is a critical
need to identify, target and manipulate specific cell populations expressing the mu-opioid …

Optogenetic is a technique that combines optics and genetics to control specific neurons.
This technique usually uses adenoviruses that encode photosensitive protein. The …

Epilepsy is a disorder in which abnormal neuronal hyperexcitation causes several types of
seizures. Because pharmacological and surgical treatments occasionally interfere with …

The brain mechanism for controlling continuous behavior in dynamic contexts must mediate
action selection and learning across many timescales, responding differentially to the level …

Cortical circuits are thought to contain a large number of cell types that coordinate to
produce behavior. Current in vivo methods rely on clustering of specified features of …

Brain perturbation studies allow detailed causal inferences of behavioral and neural
processes. Because the combination of brain perturbation methods and neural …

Sonogenetics refers to the use of genetically encoded, ultrasound-responsive mediators for
noninvasive and selective control of neural activity. It is a promising tool for studying neural …