Regulatory mechanisms and promising applications of quorum sensing-inhibiting agents in control of bacterial biofilm formation

L Zhou, Y Zhang, Y Ge, X Zhu, J Pan - Frontiers in microbiology, 2020 - frontiersin.org
A biofilm is an assemblage of microbial cells attached to a surface and encapsulated in an
extracellular polymeric substance (EPS) matrix. The formation of a biofilm is one of the …

Treatment of Pseudomonas aeruginosa infectious biofilms: Challenges and strategies

R Yin, J Cheng, J Wang, P Li, J Lin - Frontiers in Microbiology, 2022 - frontiersin.org
Pseudomonas aeruginosa, a Gram-negative bacterium, is one of the major pathogens
implicated in human opportunistic infection and a common cause of clinically persistent …

Hybrid biomimetic membrane coated particles-mediated bacterial ferroptosis for acute MRSA pneumonia

H Hu, SY Hua, X Lin, F Lu, W Zhang, L Zhou, J Cui… - ACS …, 2023 - ACS Publications
Acute methicillin resistant Staphylococcus aureus (MRSA) pneumonia is one of the most
frequently seen lung infection diseases with high morbidity and mortality. It is urgent to …

Molecular mechanisms and applications of N-acyl homoserine lactone-mediated quorum sensing in bacteria

L Kumar, SKS Patel, K Kharga, R Kumar, P Kumar… - Molecules, 2022 - mdpi.com
Microbial biodiversity includes biotic and abiotic components that support all life forms by
adapting to environmental conditions. Climate change, pollution, human activity, and natural …

Repurposing phytochemicals as anti‐virulent agents to attenuate quorum sensing‐regulated virulence factors and biofilm formation in Pseudomonas aeruginosa

J Chadha, K Harjai, S Chhibber - Microbial biotechnology, 2022 - Wiley Online Library
Unregulated consumption and overexploitation of antibiotics have paved the way for
emergence of antibiotic‐resistant strains and 'superbugs'. Pseudomonas aeruginosa is …

Plant-derived inhibitors of AHL-mediated quorum sensing in bacteria: Modes of action

D Deryabin, A Galadzhieva, D Kosyan… - International Journal of …, 2019 - mdpi.com
Numerous gram-negative phytopathogenic and zoopathogenic bacteria utilise acylated
homoserine lactone (AHL) in communication systems, referred to as quorum sensing (QS) …

Quorum sensing in food spoilage and natural-based strategies for its inhibition

I Machado, LR Silva, ED Giaouris, LF Melo… - Food Research …, 2020 - Elsevier
Food can harbor a variety of microorganisms including spoilage and pathogenic bacteria.
Many bacterial processes, including production of degrading enzymes, virulence factors …

Plant Derived Natural Products against Pseudomonas aeruginosa and Staphylococcus aureus: Antibiofilm Activity and Molecular Mechanisms

F Guzzo, M Scognamiglio, A Fiorentino, E Buommino… - Molecules, 2020 - mdpi.com
Bacteria are social organisms able to build complex structures, such as biofilms, that are
highly organized surface-associated communities of microorganisms, encased within a self …

Recent advances to combat ESKAPE pathogens with special reference to essential oils

SK Panda, S Buroni, SS Swain, A Bonacorsi… - Frontiers in …, 2022 - frontiersin.org
Biofilm-associated bacteria, especially ESKAPE pathogens (Enterococcus faecium,
Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas …

[HTML][HTML] Screening strategies for quorum sensing inhibitors in combating bacterial infections

L Lu, M Li, G Yi, L Liao, Q Cheng, J Zhu… - Journal of …, 2022 - Elsevier
Interference with quorum sensing (QS) represents an antivirulence strategy with significant
promise for the treatment of bacterial infections and a new approach for restoring antibiotic …