Due to the high number of poorly soluble drugs in the development pipeline, novel
processes for delivery of these challenging molecules are increasingly in demand. One such …

Co-amorphous (CAM) systems are promising drug-delivery systems in the arena of
therapeutic drug delivery, addressing the poor aqueous solubility of drugs by enhancing …

Leishmaniases are among the neglected tropical diseases that still cause devastating
health, social, and economic consequences to more than 350 million people worldwide …

An understanding of the structure–properties relationship of crystals is one of the principles
of crystal engineering. It is well established that the physicochemical properties of solids …

Adding NaCl to maltose depressed the glass transition temperature (T g) of freeze-dried
maltose-(dissociated) NaCl powder (by up to 9.1° C at 10% mol addition level) but did not …

Amorphous solid dispersions of polymers and drugs have been shown to improve
supersaturation maintenance of poorly water-soluble drugs. Herein, amorphous spray-dried …

Hybrid mixtures are amorphous molecular mixtures which are made up of at least two
ingredients, with at least one of which being usually found in the crystalline phase. These …

Oral administration is the most preferable route of drug delivery, especially during prolonged
therapy of chronic diseases. Unfortunately, many effective pharmaceuticals are poorly water …