Testosterone replacement therapy and cardiovascular risk
T Gagliano-Jucá, S Basaria - Nature Reviews Cardiology, 2019 - nature.com
Testosterone is the main male sex hormone and is essential for the maintenance of male
secondary sexual characteristics and fertility. Androgen deficiency in young men owing to …
secondary sexual characteristics and fertility. Androgen deficiency in young men owing to …
Dihydrotestosterone: biochemistry, physiology, and clinical implications of elevated blood levels
Benefits associated with lowered serum DHT levels after 5 α-reductase inhibitor (5AR-I)
therapy in men have contributed to a misconception that circulating DHT levels are an …
therapy in men have contributed to a misconception that circulating DHT levels are an …
Evaluation and management of testosterone deficiency: AUA guideline
JP Mulhall, LW Trost, RE Brannigan, EG Kurtz… - The Journal of …, 2018 - auajournals.org
Purpose: There has been a marked increase in testosterone prescriptions in the past
decade resulting in a growing need to give practicing clinicians proper guidance on the …
decade resulting in a growing need to give practicing clinicians proper guidance on the …
Testosterone treatment and risk of venous thromboembolism: population based case-control study
C Martinez, S Suissa, S Rietbrock, A Katholing… - bmj, 2016 - bmj.com
Objective To determine the risk of venous thromboembolism associated with use of
testosterone treatment in men, focusing particularly on the timing of the risk. Design …
testosterone treatment in men, focusing particularly on the timing of the risk. Design …
Aging and the male reproductive system
This narrative review presents an overview of current knowledge on fertility and reproductive
hormone changes in aging men, the factors driving and modulating these changes, their …
hormone changes in aging men, the factors driving and modulating these changes, their …
Association of testosterone therapy with risk of venous thromboembolism among men with and without hypogonadism
Importance Testosterone therapy is increasingly prescribed in patients without a diagnosis
of hypogonadism. This therapy may be associated with increased risk of venous …
of hypogonadism. This therapy may be associated with increased risk of venous …
Testosterone and cardiovascular health
There is an ongoing debate in the medical community regarding the effects of testosterone
on cardiovascular (CV) health. For decades, there has been conflicting evidence regarding …
on cardiovascular (CV) health. For decades, there has been conflicting evidence regarding …
Testosterone replacement therapy: for whom, when and how?
The finding of low circulating testosterone level in men is relatively frequent. The symptoms
of hypogonadism are very frequent in the aging men. However, the diagnosis of …
of hypogonadism are very frequent in the aging men. However, the diagnosis of …
Sex‐specific and hormone‐related differences in vascular remodelling in atherosclerosis
A Yerly, EPC van der Vorst… - European Journal of …, 2023 - Wiley Online Library
Atherosclerosis, a lipid‐driven inflammatory disease, is the main underlying cause of
cardiovascular diseases (CVDs) both in men and women. Sex‐related dimorphisms …
cardiovascular diseases (CVDs) both in men and women. Sex‐related dimorphisms …
Testosterone therapy and venous thromboembolism: a systematic review and meta-analysis
Background Testosterone prescribing for men has dramatically increased, and there have
been concerns about inappropriate use and adverse events. While regulatory bodies have …
been concerns about inappropriate use and adverse events. While regulatory bodies have …