Prioritization of Psychopathological Symptoms and Clinical Characterization in Psychiatric Diagnoses: A Narrative Review

S Leucht, J van Os, M Jäger, JM Davis - JAMA psychiatry, 2024 - jamanetwork.com
Importance Psychiatry mainly deals with conditions that are mediated by brain function but
are not directly attributable to specific brain abnormalities. Given the lack of concrete …

Schizophrenia spectrum disorders in children and adolescents: Clinical, phenomenological, diagnostic, and prognostic features across subtypes

M Poletti, A Raballo - Schizophrenia Research, 2024 - Elsevier
Schizophrenia spectrum disorders (SSD) typically have a diagnostically recognizable onset
in young adulthood, yet it is not unusual that help-seeking due to initial SSD-related clinical …

Quantifying the interrelationships between physical, social, and cognitive-emotional components of mental fitness using digital technology

F Iorfino, M Varidel, W Capon, M Richards… - Npj Mental Health …, 2024 - nature.com
Mental fitness is a construct that goes beyond a simple focus on subjective emotional
wellbeing to encompass more broadly our ability to think, feel, and act to achieve what we …

Are Psychiatric Nosologies Limiting the Success of Clinical Prediction Models?

I Scott, B Nelson - JAMA psychiatry, 2024 - jamanetwork.com
In many instances across psychiatric research, binary or multiclass supervised machine
learning (ML) or statistical classifiersareusedtopredictdiagnosticoutco…. Totrain and test …

Longitudinal evolution of the transdiagnostic prodrome to severe mental disorders: a dynamic temporal network analysis informed by natural language processing and …

M Arribas, JM Barnby, R Patel, RA McCutcheon… - Molecular …, 2025 - nature.com
Modelling the prodrome to severe mental disorders (SMD), including unipolar mood
disorders (UMD), bipolar mood disorders (BMD) and psychotic disorders (PSY), should …

Applying a clinical staging model in patients affected by Schizophrenia Spectrum Disorder

R de Filippis, EA Carbone, M Rania, M Aloi… - Frontiers in …, 2024 - frontiersin.org
Background Clinical staging, already widespread in medicine, represents a new frontier in
psychiatry. Our goal was to convert the existing theoretical staging model for schizophrenia …

Incorporating complexity and system dynamics into economic modelling for mental health policy and planning

P Crosland, DA Marshall, SH Hosseini, N Ho… - …, 2024 - Springer
Care as usual has failed to stem the tide of mental health challenges in children and young
people. Transformed models of care and prevention are required, including targeting the …

Early intervention in eating disorders: introducing the chronopathogram

A Preti, F Bevione, MC Lacidogna, A Raballo… - Eating and Weight …, 2025 - Springer
Eating disorders (EDs) pose significant challenges to mental and physical health,
particularly among adolescents and young adults, with the COVID-19 pandemic …

Identifying transdiagnostic psychological processes that can improve early intervention in youth mental health

TD Wade, JL Pennesi… - Australian & New Zealand …, 2025 - journals.sagepub.com
The aim of this viewpoint paper is to consider different psychological transdiagnostic
processes that can inform the development of effective early intervention approaches in …

Are indicated prevention and effective early intervention achievable goals for youth with bipolar mood disorders?

IB Hickie, EM Scott, A Ratheesh, S Cotton… - Research Directions …, 2025 - cambridge.org
Compared with other areas of mental health research that are focused on the active and
early management of youth presenting in the early stages of major mental disorders, there …