Microbial infections affect humans worldwide. Many quaternary ammonium compounds
have been synthesized that are not only antibacterial, but also possess antifungal, antiviral …

Objectives Efforts towards achieving durable resin–dentin bonds have been made for
decades, including the understanding of the mechanisms underlying hybrid layer (HL) …

Oral cavity is a gateway to the entire body and protection of this gateway is a major goal in
dentistry. Plaque biofilm is a major cause of majority of dental diseases and although …

The limited durability of resin-dentin bonds severely compromises the lifetime of tooth-
colored restorations. Bond degradation occurs via hydrolysis of suboptimally polymerized …

Effective control of oral biofilm infectious diseases represents a major global challenge.
Microorganisms in biofilms exhibit increased drug tolerance compared with planktonic cells …

Objective Success in adhesive dentistry means long lasting restorations. However, there is
substantial evidence that this ideal objective is not always achieved. Current research in this …

Hard tissue repair and regeneration cost hundreds of billions of dollars annually worldwide,
and the need has substantially increased as the population has aged. Hard tissues include …

Adhesive systems are resin-based materials that reach their final mechanical properties
through a polymerization process. Previous literature correlated the failure of the adhesive …

Objective Endogenous dentin collagenolytic enzymes, matrix metalloproteinases (MMPs)
and cysteine cathepsins, are responsible for the time-dependent hydrolysis of collagen …

This review examines the fundamental processes responsible for the aging mechanisms
involved in the degradation of resin‐bonded interfaces, as well as some potential …