Simple Summary Three-dimensional (3D) cell culture models have been proposed as
alternatives for initial drug screening to increase drug development efficiency. In addition to …

Cancer immunotherapy is the great breakthrough in cancer treatment as it displayed
prolonged progression-free survival over conventional therapies, yet, to date, in only a …

In crowded microenvironments, migrating cells must find or make a path. Amoeboid cells are
thought to find a path by deforming their bodies to squeeze through tight spaces. Yet, some …

Tunable bioprinting materials are capable of creating a broad spectrum of physiological
mimicking 3D models enabling in vitro studies that more accurately resemble in vivo …

Despite the efforts devoted to drug discovery and development, the number of new drug
approvals have been decreasing. Specifically, cardiovascular developments have been …

Melanoma is recognized as the most dangerous type of skin cancer, with high mortality and
resistance to currently used treatments. To overcome the limitations of the available …

We introduce a cost-effective and easily implementable scan unit that converts any camera-
based microscope with optical sectioning capability into a multi-angle projection imaging …

Tissue microenvironments affect the functional states of cancer cells, but determining these
influences in vivo has remained a challenge. We present a quantitative high-resolution …

One of the main prerequisites to quality of a biomaterial for clinical use is the biocompatibility
evaluation at the cellular and tissue levels. The primary and mandatory element in …

Cell image classification methods are currently being used in numerous applications in cell
biology and medicine. Applications include understanding the effects of genes and drugs in …