The global emergence of zoonotic viruses, including poxviruses, poses one of the greatest
threats to human and animal health. Forty years after the eradication of smallpox, emerging …

Among the Poxviridae family, orthopoxvirus is the most notorious genus. Several DNA
viruses belonging to this group are known to produce human disease from the life …

Skin disease due to viruses may be a primary infection of the epidermis or may arise
secondary to systemic infection. Depending on the virus, the effects may be necrotic damage …

Poxviruses compromise a group of long known important pathogens including some
zoonotic members affecting lifestock animals and humans. While whole genome sequence …

On May 8, 1980, the World Health Assembly at its 33rd session solemnly declared that the
world and all its peoples had won freedom from smallpox and recommended ceasing the …

Forty years after the last endemic smallpox case, variola virus (VARV) is still considered a
major threat to humans due to its possible use as a bioterrorism agent. For many years, the …

The Orthopoxvirus genus, especially variola virus (VARV), monkeypox virus (MPXV),
remains a significant public health threat worldwide. The development of therapeutic …

To support the licensure of a new and safer vaccine to protect people against smallpox, a
monkeypox model of infection in cynomolgus macaques, which simulates smallpox in …

The question of the origin of smallpox, one of the major menaces to humankind, is a
constant concern for the scientific community. Smallpox is caused by the agent referred to as …

Smallpox was one of the most devastating diseases known to humanity. Although smallpox
was eradicated through a historically successful vaccination campaign, there is concern in …