Meta‐Analysis of Alterations in Regulatory T Cells' Frequency and Suppressive Capacity in Patients with Vitiligo

PS Giri, J Mistry, M Dwivedi - Journal of Immunology Research, 2022 - Wiley Online Library
Vitiligo is a noncontagious autoimmune skin depigmenting disease. Regulatory T cells
(Tregs) play a key role in maintaining peripheral tolerance; however, Tregs' number …

Engineered antigen-specific regulatory T cells for autoimmune skin conditions

Z Mukhatayev, YO Ostapchuk, D Fang, IC Le Poole - Autoimmunity reviews, 2021 - Elsevier
Regulatory T cells (Tregs) are a subset of T cells responsible for the regulation of immune
responses, thereby maintaining immune homeostasis and providing immune tolerance to …

Neutrophil to lymphocyte ratio in patients with vitiligo

B Solak, BS Dikicier, NC Cosansu… - Advances in Dermatology …, 2017 - termedia.pl
Aim: To investigate whether systemic inflammation is increased in vitiligo patients in a case-
control study design. Material and methods: Nonsegmental vitiligo patients who had been …

Predominant role of innate pro-inflammatory cytokines in vitiligo disease

N Gholijani, MR Yazdani, L Dastgheib - Archives of dermatological …, 2020 - Springer
Vitiligo is a skin disorder with melanocyte destruction and an autoimmune basis. Given the
importance of cytokines in autoimmunity, we aimed to find the cytokine profile of innate and …

The skin delivery of tofacitinib citrate using transethosomes and hybridized ethosomes/nanostructured lipid carriers for vitiligo therapy: Dermatopharmacokinetics and …

H Hesham, M Rady, RM Hathout, M Abdel-Halim… - International Journal of …, 2022 - Elsevier
Vitiligo is an autoimmune disease where its current treatment strategies are lengthy in
course and do not guarantee complete cure. Tofacitinib citrate (JAK inhibitor) is a potential …

Decreased suppression of CD8+ and CD4+ T cells by peripheral regulatory T cells in generalized vitiligo due to reduced NFATC1 and FOXP3 proteins

PS Giri, M Dwivedi, R Begum - Experimental Dermatology, 2020 - Wiley Online Library
Regulatory T cells (Tregs) are involved in the suppression of activated T cells in generalized
vitiligo (GV). The study was aimed to investigate Tregs functional defects in Treg: CD8+ and …

Altered expression of nuclear factor of activated T cells, forkhead box P3, and immune‐suppressive genes in regulatory T cells of generalized vitiligo patients

PS Giri, M Dwivedi, NC Laddha… - Pigment Cell & …, 2020 - Wiley Online Library
The study was aimed to analyze expression of nuclear factor of activated T cells (NFATs),
forkhead box P3 (FOXP3), and their associated genes (sCTLA4, flCTLA4, IL10, TGFB, IL2 …

Can monocyte to HDL cholesterol ratio and monocyte to lymphocyte ratio be markers for inflammation and oxidative stress in patients with vitiligo? A preliminary study

A Demirbaş, ÖF Elmas, M Atasoy, Ü Türsen… - Archives of …, 2021 - Springer
Both systemic inflammation and oxidative stress play crucial roles in the pathogenesis of
vitiligo. In recent studies, monocyte to high-density lipoprotein cholesterol ratio (MHR) …

Biomarkers of disease activity in vitiligo: A systematic review

R Speeckaert, M Speeckaert, S De Schepper… - Autoimmunity …, 2017 - Elsevier
The pathophysiology of vitiligo is complex although recent research has discovered several
markers which are linked to vitiligo and associated with disease activity. Besides providing …

CXCL‐10 and Interleukin‐6 are reliable serum markers for vitiligo activity: A multicenter cross‐sectional study

M Abdallah, M El‐Mofty, T Anbar… - Pigment cell & …, 2018 - Wiley Online Library
This cross‐sectional multicenter study aimed to evaluate serum CXCL‐10, as an activity
marker for vitiligo, and compare it with other putative serum and tissue markers. Serum …