NAMPT and NAPRT: two metabolic enzymes with key roles in inflammation
Nicotinamide phosphoribosyltransferase (NAMPT) and nicotinate
phosphoribosyltransferase (NAPRT) are two intracellular enzymes that catalyze the first step …
phosphoribosyltransferase (NAPRT) are two intracellular enzymes that catalyze the first step …
Adipose tissue angiogenesis as a therapeutic target for obesity and metabolic diseases
Y Cao - Nature reviews Drug discovery, 2010 - nature.com
Current pharmacotherapeutic options for treating obesity and related metabolic disorders
remain limited and ineffective. Emerging evidence shows that modulators of angiogenesis …
remain limited and ineffective. Emerging evidence shows that modulators of angiogenesis …
Adropin is a novel regulator of endothelial function
Background—Adropin is a recently identified protein that has been implicated in the
maintenance of energy homeostasis and insulin resistance. Because vascular function and …
maintenance of energy homeostasis and insulin resistance. Because vascular function and …
Osteogenesis and angiogenesis induced by porous β-CaSiO3/PDLGA composite scaffold via activation of AMPK/ERK1/2 and PI3K/Akt pathways
C Wang, K Lin, J Chang, J Sun - Biomaterials, 2013 - Elsevier
As a potential bioactive material, β-calcium silicate (β-CS) has attracted particular attention
in the field of bone regeneration. In this study, porous β-CS/Poly-d, l-Lactide-Glycolide …
in the field of bone regeneration. In this study, porous β-CS/Poly-d, l-Lactide-Glycolide …
Uric acid induces endothelial dysfunction by vascular insulin resistance associated with the impairment of nitric oxide synthesis
Endothelial dysfunction is defined as impairment of the balance between endothelium‐
dependent vasodilation and constriction. Despite evidence of uric acid‐induced endothelial …
dependent vasodilation and constriction. Despite evidence of uric acid‐induced endothelial …
Inflammation and metabolic dysfunction: links to cardiovascular diseases
A Taube, R Schlich, H Sell… - American journal of …, 2012 - journals.physiology.org
Abdominal obesity is a major risk factor for cardiovascular disease, and recent studies
highlight a key role of adipose tissue dysfunction, inflammation, and aberrant adipokine …
highlight a key role of adipose tissue dysfunction, inflammation, and aberrant adipokine …
Visfatin/Nampt: an adipokine with cardiovascular impact
T Romacho, CF Sánchez-Ferrer… - Mediators of …, 2013 - Wiley Online Library
Adipose tissue is acknowledged as an endocrine organ that releases bioactive factors
termed adipokines. Visfatin was initially identified as a novel adipokine with insulin‐mimetic …
termed adipokines. Visfatin was initially identified as a novel adipokine with insulin‐mimetic …
Adipokines: biofactors from white adipose tissue. A complex hub among inflammation, metabolism, and immunity
Until the identification of leptin, the first adipokine discovered in 1994, adipose tissue was
considered only as an energy storage tissue. However, it is now clear that adipose tissue is …
considered only as an energy storage tissue. However, it is now clear that adipose tissue is …
Extracellular nicotinamide phosphoribosyltransferase, a new cancer metabokine
In this review, we focus on the secreted form of nicotinamide phosphoribosyltransferase
(NAMPT); extracellular NAMPT (eNAMPT), also known as pre‐B cell colony‐enhancing …
(NAMPT); extracellular NAMPT (eNAMPT), also known as pre‐B cell colony‐enhancing …
Mechanism overview and target mining of atherosclerosis: Endothelial cell injury in atherosclerosis is regulated by glycolysis
R Wang, M Wang, J Ye, G Sun… - … journal of molecular …, 2021 - spandidos-publications.com
Atherosclerosis (AS) is a chronic disease with a complex pathology that may lead to several
cardiovascular and cerebrovascular diseases; however, further research is necessary to …
cardiovascular and cerebrovascular diseases; however, further research is necessary to …