Wound healing is a complex process that involves the coordinated actions of many different
tissues and cell lineages. It requires tight orchestration of cell migration, proliferation, matrix …

The cellular and molecular mechanisms underpinning tissue repair and its failure to heal are
still poorly understood, and current therapies are limited. Poor wound healing after trauma …

A considerable understanding of the fundamental cellular and molecular mechanisms
underpinning healthy acute wound healing has been gleaned from studying various animal …

The epithelial-mesenchymal transition (EMT) describes the global process by which
stationary epithelial cells undergo phenotypic changes, including the loss of cell-cell …

Uncontrolled cell survival, growth, angiogenesis and metastasis are essential hallmarks of
cancer. Genetic and biochemical data have demonstrated that the growth and motility factor …

Wounds in diabetic patients, especially diabetic foot ulcers, are more difficult to heal
compared with normal wounds and can easily deteriorate, leading to amputation. Common …

The MET tyrosine kinase receptor (also known as the HGF receptor) promotes tissue
remodelling, which underlies developmental morphogenesis, wound repair, organ …

The repair of wounds is one of the most complex biological processes that occur during
human life. After an injury, multiple biological pathways immediately become activated and …

Purpose The phase III OAM4971g study (METLung) examined the efficacy and safety of
onartuzumab plus erlotinib in patients with locally advanced or metastatic non–small-cell …

Liver regeneration after partial hepatectomy is a very complex and well‐orchestrated
phenomenon. It is carried out by the participation of all mature liver cell types. The process is …