Decoding the brain: From neural representations to mechanistic models

MW Mathis, AP Rotondo, EF Chang, AS Tolias… - Cell, 2024 - cell.com
A central principle in neuroscience is that neurons within the brain act in concert to produce
perception, cognition, and adaptive behavior. Neurons are organized into specialized brain …

The science and engineering behind sensitized brain-controlled bionic hands

C Pandarinath, SJ Bensmaia - Physiological Reviews, 2022 - journals.physiology.org
Advances in our understanding of brain function, along with the development of neural
interfaces that allow for the monitoring and activation of neurons, have paved the way for …

Learnable latent embeddings for joint behavioural and neural analysis

S Schneider, JH Lee, MW Mathis - Nature, 2023 - nature.com
Map** behavioural actions to neural activity is a fundamental goal of neuroscience. As our
ability to record large neural and behavioural data increases, there is growing interest in …

Rastermap: a discovery method for neural population recordings

C Stringer, L Zhong, A Syeda, F Du, M Kesa… - Nature …, 2024 - nature.com
Neurophysiology has long progressed through exploratory experiments and chance
discoveries. Anecdotes abound of researchers listening to spikes in real time and noticing …

A unified, scalable framework for neural population decoding

M Azabou, V Arora, V Ganesh, X Mao… - Advances in …, 2024 - proceedings.neurips.cc
Our ability to use deep learning approaches to decipher neural activity would likely benefit
from greater scale, in terms of both the model size and the datasets. However, the …

A large-scale neural network training framework for generalized estimation of single-trial population dynamics

MR Keshtkaran, AR Sedler, RH Chowdhury… - Nature …, 2022 - nature.com
Achieving state-of-the-art performance with deep neural population dynamics models
requires extensive hyperparameter tuning for each dataset. AutoLFADS is a model-tuning …

Dynamical flexible inference of nonlinear latent factors and structures in neural population activity

H Abbaspourazad, E Erturk, B Pesaran… - Nature Biomedical …, 2024 - nature.com
Modelling the spatiotemporal dynamics in the activity of neural populations while also
enabling their flexible inference is hindered by the complexity and noisiness of neural …

The sensorium competition on predicting large-scale mouse primary visual cortex activity

KF Willeke, PG Fahey, M Bashiri, L Pede… - arxiv preprint arxiv …, 2022 - arxiv.org
The neural underpinning of the biological visual system is challenging to study
experimentally, in particular as the neuronal activity becomes increasingly nonlinear with …

Stabilizing brain-computer interfaces through alignment of latent dynamics

BM Karpowicz, YH Ali, LN Wimalasena, AR Sedler… - BioRxiv, 2022 - biorxiv.org
Intracortical brain-computer interfaces (iBCIs) restore motor function to people with paralysis
by translating brain activity into control signals for external devices. In current iBCIs …

Aligned and oblique dynamics in recurrent neural networks

F Schuessler, F Mastrogiuseppe, S Ostojic, O Barak - eLife, 2024 - elifesciences.org
The relation between neural activity and behaviorally relevant variables is at the heart of
neuroscience research. When strong, this relation is termed a neural representation. There …