Dodging the host interferon-stimulated gene mediated innate immunity by HIV-1: a brief update on intrinsic mechanisms and counter-mechanisms
K Chintala, K Mohareer, S Banerjee - Frontiers in Immunology, 2021 - frontiersin.org
Host restriction factors affect different phases of a viral life cycle, contributing to innate
immunity as the first line of defense against viruses, including HIV-1. These restriction factors …
immunity as the first line of defense against viruses, including HIV-1. These restriction factors …
Retroviral restriction factors and their viral targets: restriction strategies and evolutionary adaptations
G Boso, CA Kozak - Microorganisms, 2020 - mdpi.com
The evolutionary conflict between retroviruses and their vertebrate hosts over millions of
years has led to the emergence of cellular innate immune proteins termed restriction factors …
years has led to the emergence of cellular innate immune proteins termed restriction factors …
Insights into the structures and multimeric status of APOBEC proteins involved in viral restriction and other cellular functions
XS Chen - Viruses, 2021 - mdpi.com
Apo lipoprotein B mRNA e diting c atalytic polypeptide-like (APOBEC) proteins belong to a
family of deaminase proteins that can catalyze the deamination of cytosine to uracil on …
family of deaminase proteins that can catalyze the deamination of cytosine to uracil on …
Deaminase-independent mode of antiretroviral action in human and mouse APOBEC3 proteins
Y Hakata, M Miyazawa - Microorganisms, 2020 - mdpi.com
Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3 (APOBEC3) proteins
(APOBEC3s) are deaminases that convert cytosines to uracils predominantly on a single …
(APOBEC3s) are deaminases that convert cytosines to uracils predominantly on a single …
[HTML][HTML] Engineered CBEs based on Macaca fascicularis A3A with improved properties for precise genome editing
CY Ren, YS Liu, YS He, LP Zhang, JH Rao, Y Rao… - Cell Reports, 2024 - cell.com
Cytidine deaminase defines the properties of cytosine base editors (CBEs) for C-to-T
conversion. Replacing the cytidine deaminase rat APOBEC1 (rA1) in CBEs with a human …
conversion. Replacing the cytidine deaminase rat APOBEC1 (rA1) in CBEs with a human …
Encapsidation of staufen-2 enhances infectivity of hiv-1
Staufen, the RNA-binding family of proteins, affects various steps in the Human Immuno-
Deficiency Virus (HIV-1) replication cycle. While our previous study established Staufen-2 …
Deficiency Virus (HIV-1) replication cycle. While our previous study established Staufen-2 …
Ocular A-to-I RNA editing signatures associated with SARS-CoV-2 infection
YY **, YP Liang, WH Huang, L Guo, LL Cheng… - BMC genomics, 2024 - Springer
Ophthalmic manifestations have recently been observed in acute and post-acute
complications of COVID-19 caused by SARS-CoV-2 infection. Our precious study has shown …
complications of COVID-19 caused by SARS-CoV-2 infection. Our precious study has shown …
Foamy Viruses, Bet, and APOBEC3 Restriction
Non-human primates (NHP) are an important source of viruses that can spillover to humans
and, after adaptation, spread through the host population. Whereas HIV-1 and HTLV-1 …
and, after adaptation, spread through the host population. Whereas HIV-1 and HTLV-1 …
[HTML][HTML] Divergence in dimerization and activity of primate APOBEC3C
Abstract The APOBEC3 (A3) family of single-stranded DNA cytidine deaminases are host
restriction factors that inhibit lentiviruses, such as HIV-1, in the absence of the Vif protein that …
restriction factors that inhibit lentiviruses, such as HIV-1, in the absence of the Vif protein that …
[HTML][HTML] Murine leukemia virus resists producer cell APOBEC3A by its Glycosylated Gag but not target cell APOBEC3A
Abstract The human APOBEC3A (A3A) polynucleotide cytidine deaminase has been shown
to have antiviral activity against HTLV-1 but not HIV-1, when expressed in the virus producer …
to have antiviral activity against HTLV-1 but not HIV-1, when expressed in the virus producer …