microRNA biosensors: Opportunities and challenges among conventional and commercially available techniques

T Kilic, A Erdem, M Ozsoz, S Carrara - Biosensors and Bioelectronics, 2018 - Elsevier
As being the most extensively studied, non-coding, evolutionary conserved, post-
transcriptional gene regulators of genome, microRNAs (miRNAs) have taken great attention …

MicroRNAs in B-cell lymphomas: how a complex biology gets more complex

K Musilová, M Mráz - Leukemia, 2015 - nature.com
MicroRNAs (miRNAs) represent important regulators of gene expression besides
transcriptional control. miRNA regulation can be involved in the cell developmental fate …

Cobomarsen, an Oligonucleotide Inhibitor of miR-155, Slows DLBCL Tumor Cell Growth In Vitro and In Vivo

E Anastasiadou, AG Seto, X Beatty… - Clinical Cancer …, 2021 - aacrjournals.org
Purpose: miRNA-155 is an oncogenic miRNA highly expressed in B-cell malignancies,
particularly in the non–germinal center B-cell or activated B-cell subtype of diffuse large B …

Epstein− Barr virus-encoded EBNA2 alters immune checkpoint PD-L1 expression by downregulating miR-34a in B-cell lymphomas

E Anastasiadou, D Stroopinsky, S Alimperti, AL Jiao… - Leukemia, 2019 - nature.com
Cancer cells subvert host immune surveillance by altering immune checkpoint (IC) proteins.
Some Epstein− Barr virus (EBV)-associated tumors have higher Programmed Cell Death …

EBV-positive diffuse large B-cell lymphoma of the elderly

CY Ok, TG Papathomas, LJ Medeiros… - Blood, The Journal of …, 2013 - ashpublications.org
Epstein-Barr virus (EBV) positive diffuse large B-cell lymphoma (DLBCL) of the elderly,
initially described in 2003, is a provisional entity in the 2008 World Health Organization …

Targeting miR-21 Inhibits In Vitro and In Vivo Multiple Myeloma Cell Growth

E Leone, E Morelli, MT Di Martino… - Clinical Cancer …, 2013 - aacrjournals.org
Purpose: Deregulated expression of miRNAs plays a role in the pathogenesis and
progression of multiple myeloma. Among upregulated miRNAs, miR-21 has oncogenic …

Epstein-Barr virus oncoprotein super-enhancers control B cell growth

H Zhou, SCS Schmidt, S Jiang, B Willox, K Bernhardt… - Cell host & …, 2015 - cell.com
Super-enhancers are clusters of gene-regulatory sites bound by multiple transcription
factors that govern cell transcription, development, phenotype, and oncogenesis. By …

[HTML][HTML] MicroRNAs: small but key players in viral infections and immune responses to viral pathogens

AN Bauer, N Majumdar, F Williams, S Rajput… - Biology, 2023 - mdpi.com
Simple Summary Viral outbreaks continue to be an obstacle to human health, with the
Severe Acute Respiratory Syndrome-related Coronavirus (SARS-CoV-2) pandemic …

Emerging microRNAs in cancer diagnosis, progression, and immune surveillance

AM Harrandah, RA Mora, EKL Chan - Cancer letters, 2018 - Elsevier
MicroRNAs (miRNAs) are small noncoding RNAs that function in post-transcriptional
regulation of gene expression. Dysregulation of miRNAs has been reported in different …

EBV-driven B-cell lymphoproliferative disorders: from biology, classification and differential diagnosis to clinical management

CY Ok, L Li, KH Young - Experimental & Molecular Medicine, 2015 - nature.com
Epstein–Barr virus (EBV) is a ubiquitous herpesvirus, affecting> 90% of the adult population.
EBV targets B-lymphocytes and achieves latent infection in a circular episomal form …