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Pre-eclampsia: pathophysiology and clinical implications
GJ Burton, CW Redman, JM Roberts, A Moffett - Bmj, 2019 - bmj.com
Pre-eclampsia is a common disorder that particularly affects first pregnancies. The clinical
presentation is highly variable but hypertension and proteinuria are usually seen. These …
presentation is highly variable but hypertension and proteinuria are usually seen. These …
Combining biomarkers to predict pregnancy complications and redefine preeclampsia: the angiogenic-placental syndrome
H Stepan, M Hund, T Andraczek - Hypertension, 2020 - ahajournals.org
Placental dysfunction underlies a spectrum of perinatal pathologies, including preeclampsia
and fetal growth restriction. Angiogenesis-related factors, including sFlt-1 (soluble fms-like …
and fetal growth restriction. Angiogenesis-related factors, including sFlt-1 (soluble fms-like …
[HTML][HTML] Oxidative stress and mitochondrial dysfunction in early-onset and late-onset preeclampsia
Preeclampsia is a pregnancy-specific syndrome with multisystem involvement which leads
to foetal, neonatal, and maternal morbidity and mortality. This syndrome is characterized by …
to foetal, neonatal, and maternal morbidity and mortality. This syndrome is characterized by …
Mechanisms of endothelial dysfunction in pre-eclampsia and gestational diabetes mellitus: windows into future cardiometabolic health?
Placental insufficiency and adipose tissue dysregulation are postulated to play key roles in
the pathophysiology of both pre-eclampsia (PE) and gestational diabetes mellitus (GDM). A …
the pathophysiology of both pre-eclampsia (PE) and gestational diabetes mellitus (GDM). A …
Clinical utility of sFlt‐1 and PlGF in screening, prediction, diagnosis and monitoring of pre‐eclampsia and fetal growth restriction
H Stepan, A Galindo, M Hund… - … in Obstetrics & …, 2023 - Wiley Online Library
Pre‐eclampsia (PE) is characterized by placental and maternal endothelial dysfunction, and
associated with fetal growth restriction (FGR), placental abruption, preterm delivery and …
associated with fetal growth restriction (FGR), placental abruption, preterm delivery and …
Prediction models for preeclampsia: A systematic review
Background Preeclampsia is a disease specific to pregnancy that can cause severe
maternal and foetal morbidity and mortality. Early identification of women at higher risk for …
maternal and foetal morbidity and mortality. Early identification of women at higher risk for …
The prediction of early preeclampsia: Results from a longitudinal proteomics study
Objectives To identify maternal plasma protein markers for early preeclampsia (delivery< 34
weeks of gestation) and to determine whether the prediction performance is affected by …
weeks of gestation) and to determine whether the prediction performance is affected by …
The prediction of late-onset preeclampsia: Results from a longitudinal proteomics study
Background Late-onset preeclampsia is the most prevalent phenotype of this syndrome;
nevertheless, only a few biomarkers for its early diagnosis have been reported. We sought to …
nevertheless, only a few biomarkers for its early diagnosis have been reported. We sought to …
The ROBINS‐I and the NOS had similar reliability but differed in applicability: a random sampling observational studies of systematic reviews/meta‐analysis
Y Zhang, L Huang, D Wang, P Ren… - Journal of Evidence …, 2021 - Wiley Online Library
Objective There is a lack of evidence on the usage of the quality assessment tool‐the Risk
Of Bias In Nonrandomized Studies‐of Interventions (ROBINS‐I). This article aimed to …
Of Bias In Nonrandomized Studies‐of Interventions (ROBINS‐I). This article aimed to …
Predictive value of the sFlt-1/PlGF ratio in women with suspected preeclampsia: An update
A Velegrakis, E Kouvidi… - International …, 2023 - spandidos-publications.com
Preeclampsia (PE) is a major complication of pregnancy with an incidence rate of 2-8% and
is a leading cause of maternal mortality and morbidity. The various consequences of severe …
is a leading cause of maternal mortality and morbidity. The various consequences of severe …