Fatigue, depression, and pain affect the majority of multiple sclerosis (MS) patients, which
causes a substantial burden to patients and society. The pathophysiology of these …

Fatigue and depression are common conditions diagnosed in people with multiple sclerosis
(MS). Fatigue defined as subjective lack of physical and/or mental energy is present in 35 …

Drowsiness is a state of fatigue or sleepiness characterized by a strong urge to sleep. It is
correlated with a progressive decline in response time, compromised processing of …

Background and purpose The prevalence of fatigue and its relation with clinical,
neuropsychological and brain magnetic resonance imaging (MRI) variables in a large cohort …

Fatigue is one of the most disabling symptoms of multiple sclerosis (MS); it influences
patients' quality of life. The etiology of fatigue is complex, and its pathogenesis is still unclear …

Introduction Fatigue, cognitive impairment, depression, and pain are highly prevalent
symptoms in multiple sclerosis (MS). These often co-occur and may be explained by a …

Background Somatic depression (SD) is different from non-somatic depression (NSD), and
insular subregions have been associated with somatic symptoms. However, the pattern of …

The last decade has seen the emergence of new theoretical frameworks to explain
pathological fatigue, a much neglected, yet highly significant symptom across a wide range …

Cognitive fatigue is common and debilitating among persons with multiple sclerosis (pwMS).
Neural mechanisms underlying fatigue are not well understood, which results in lack of …

Background Besides demographics and clinical factors, psychological variables and brain-
tissue changes have been associated with fatigue in persons with multiple sclerosis (pwMS) …