Environmental pollution is escalating due to rapid global development that often prioritizes
human needs over planetary health. Despite global efforts to mitigate legacy pollutants, the …

Burkholderia pseudomallei, the causative agent of melioidosis, is found in soil and water of
tropical and subtropical regions globally. Modelled estimates of the global burden predict …

Summary Background The Global Burden of Diseases, Injuries, and Risk Factors Study
2017 (GBD 2017) includes a comprehensive assessment of incidence, prevalence, and …

Background As mortality rates decline, life expectancy increases, and populations age, non-
fatal outcomes of diseases and injuries are becoming a larger component of the global …

Burkholderia pseudomallei is a Gram-negative environmental bacterium and the
aetiological agent of melioidosis, a life-threatening infection that is estimated to account …

Background The global distribution of melioidosis is under considerable scrutiny, with both
unmasking of endemic disease in African and Pacific nations and evidence of more recent …

Cyclic guanosine monophosphate (GMP)-adenosine monophosphate (AMP)(cGAMP)
synthase (cGAS), along with the adaptor stimulator of interferon genes (STING), are crucial …

Bacillus anthracis is a spore-forming, Gram-positive bacterium responsible for anthrax, an
acute infection that most significantly affects grazing livestock and wild ungulates, but also …

Melioidosis, caused by Burkholderia pseudomallei, is a rare but potentially fatal bacterial
disease endemic to tropical and subtropical regions worldwide. It is typically acquired …

Burkholderia cepacia (formerly Pseudomonas cepacia) was once thought to be a single
bacterial species but has expanded to the Burkholderia cepacia complex (Bcc), comprising …