Stimulus-cleavable nanoscale drug delivery systems are receiving significant attention
owing to their capability of achieving exquisite control over drug release via the exposure to …

Photoremovable Protecting Groups in Chemistry and Biology: Reaction Mechanisms and
Efficacy | Chemical Reviews Recently Viewedclose modal ACS ACS Publications C&EN CAS …

Pharmacotherapy is often severely hindered by issues related to poor drug selectivity,
including side effects, environmental toxicity, and the emergence of resistance. Lack of …

Targeted drug delivery refers to an established therapeutic strategy that develops platforms
and nanoscale devices for selective delivery of small drug molecules and therapeutic genes …

Polymeric micelles (PM) system, as an efficient drug carrier, has received growing scientific
attention in recent years owing to its solubilization, selective targeting, P-glycoprotein …

The combination of highly efficient polymerizations with modular “click” coupling reactions
has enabled the synthesis of a wide variety of novel nanoscopic structures. Here we …

The current available therapeutics face several challenges such as the development of ideal
drug delivery systems towards the goal of personalized treatments for patients benefit. The …

Most applications of photoremovable protecting groups have used o-nitrobenzyl compounds
and their (often commercially available) derivatives that, however, have several …

The small and synthetically easily accessible coumarinylmethyl backbone has been
modified to generate a family of photolabile protecting groups with redshifted absorption. We …

Paclitaxel (Taxol®, PTX) is a promising anti-cancer drug and has been successfully used to
treat a wide variety of cancers. Unfortunately, serious clinical side effects are associated with …