Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

JA Welsh, DCI Goberdhan, L O'Driscoll… - Journal of …, 2024 - Wiley Online Library
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …

Integrating organs-on-chips: multiplexing, scaling, vascularization, and innervation

DY Park, J Lee, JJ Chung, Y Jung, SH Kim - Trends in biotechnology, 2020 - cell.com
Organs-on-chips (OoCs) have attracted significant attention because they can be designed
to mimic in vivo environments. Beyond constructing a single OoC, recent efforts have tried to …

CRISPR-cas9 genome editing delivery systems for targeted cancer therapy

A Ghaemi, E Bagheri, K Abnous, SM Taghdisi… - Life sciences, 2021 - Elsevier
The prokaryotic CRISPR–Cas systems could be applied as revolutionized genome editing
tool in live cells of various species to modify, visualize and identify definite sequences of …

Activation of the receptor tyrosine kinase AXL regulates the immune microenvironment in glioblastoma

H Sadahiro, KD Kang, JT Gibson, M Minata, H Yu, J Shi… - Cancer research, 2018 - AACR
Glioblastoma (GBM) is a lethal disease with no effective therapies available. We previously
observed upregulation of the TAM (Tyro-3, Axl, and Mer) receptor tyrosine kinase family …

[HTML][HTML] Electrochemical integrated paper-based immunosensor modified with multi-walled carbon nanotubes nanocomposites for point-of-care testing of 17β …

Y Wang, J Luo, J Liu, X Li, Z Kong, H **… - Biosensors and …, 2018 - Elsevier
Abstract 17β-estradiol (17β-E2) plays a critical role in regulating reproduction in human,
there is therefore an urgent need to detect it sensitively and precisely in a cost-effective and …

[HTML][HTML] GAS5 suppresses malignancy of human glioma stem cells via a miR-196a-5p/FOXO1 feedback loop

X Zhao, Y Liu, J Zheng, X Liu, J Chen, L Liu… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Glioma stem cells (GSCs) make up highly tumorigenic subpopulations within gliomas, and
aberrant expression of GSC genes is a major underlying cause of glioma pathogenesis and …

High throughput and highly controllable methods for in vitro intracellular delivery

J Brooks, G Minnick, P Mukherjee, A Jaberi, L Chang… - Small, 2020 - Wiley Online Library
In vitro and ex vivo intracellular delivery methods hold the key for releasing the full potential
of tissue engineering, drug development, and many other applications. In recent years, there …

DNA nanomachines for identifying cancer biomarkers in body fluids and cells

Z Dong, X Xue, H Liang, J Guan, L Chang - Analytical Chemistry, 2020 - ACS Publications
Identifying molecular biomarkers promises to significantly improve the accuracy in cancer
diagnosis at its early stage. DNA nanomachines, which are designable and switchable …

Combating cancer stem-like cell-derived resistance to anticancer protein by liposome-mediated acclimatization strategy

S Shen, S Lin, Y Chen, Y Zhang, Y He, X Xu… - Nano Letters, 2022 - ACS Publications
Antibody-based therapeutics, which induce apoptosis of malignant cells by selectively
binding to their receptors, hold tremendous promise for clinical cancer therapy. Tumor …

Molecular beacon nano-sensors for probing living cancer cells

T Kuang, L Chang, X Peng, X Hu… - Trends in …, 2017 - cell.com
Heterogeneities and oncogenesis essentially result from proteomic disorders orchestrated
by changes in DNA and/or cytoplasmic mRNA. These genetic fluctuations, however, cannot …