Mechanistic insights into circRNA-mediated regulation of PI3K signaling pathway in glioma progression

A Mafi, SM Khoshnazar, A Shahpar, N Nabavi… - … -Research and Practice, 2024 - Elsevier
Abstract Circular RNAs (CircRNAs) are non-coding RNAs (ncRNAs) characterized by a
stable circular structure that regulates gene expression at both transcriptional and post …

[HTML][HTML] Flavonoids as modulators of miRNA expression in pancreatic cancer: Pathways, Mechanisms, And Therapeutic Potential

H Helen, MC Gunawan, P Halim, MR Dinata… - Biomedicine & …, 2024 - Elsevier
Pancreatic cancer (PC) is a complex malignancy, distinguished by its aggressive
characteristics and unfavorable prognosis. Recent developments in understanding the …

[HTML][HTML] Development and validation of a prognostic and drug sensitivity model for gastric cancer utilizing telomere-related genes

X Li, X Wang, F Yu, Z Li, D Chen, Y Qi, Z Lu, Y Liu… - Translational …, 2025 - Elsevier
Background Gastric cancer (GC) poses a major global health challenge because of its
unfavorable prognosis. Elevated telomerase activity has been linked to the rapid growth and …

Exosomal PSM-E inhibits macrophage M2 polarization to suppress prostate cancer metastasis through the RACK1 signaling axis

X Qin, R Niu, Y Tan, Y Huang, W Ren, W Zhou, H Wu… - Biomarker …, 2024 - Springer
Background It is well-established that understanding the mechanism of prostate cancer
(PCa)-associated metastasis is paramount for improving its prognosis. Metastasis is known …

Circular RNAs and cervical cancer: friends or foes? A landscape on circRNA-mediated regulation of key signaling pathways involved in the onset and progression of …

E Heydarnia, Z Dorostgou, N Hedayati… - Cell Communication and …, 2024 - Springer
Cervical cancer (CC) is a common gynecologic malignancy, accounting for a significant
proportion of women death worldwide. Human papillomavirus (HPV) infection is one of the …

Navigating the brain: the role of exosomal shuttles in precision therapeutics

S Fatima, A Qaiser, S Andleeb, AH Hashmi… - Frontiers in …, 2024 - frontiersin.org
Brain diseases have become one of the leading roots of mortality and disability worldwide,
contributing a significant part of the disease burden on healthcare systems. The blood-brain …

MicroRNA dysregulation and its impact on apoptosis-related signaling pathways in myelodysplastic syndrome

N Hedayati, MS Naeini, MMA Sahebfosoul… - … -Research and Practice, 2024 - Elsevier
Myelodysplastic syndrome (MDS) holds a unique position among blood cancers,
encompassing a spectrum of blood-related disorders marked by impaired maturation of …

Regulatory role of PPAR in colorectal cancer

C Wang, T Lv, B **, Y Li, Z Fan - Cell Death Discovery, 2025 - nature.com
Colorectal cancer (CRC) is one of the most common tumors in the digestive system, and the
majority of patients are found to be in advanced stages, which is a burden to human health …

Evolving landscape of detection and targeting miRNA/epigenetics for therapeutic strategies in ovarian cancer

AD Bhowmik, P Shaw, MSG Pillai, G Rao, SKD Dwivedi - Cancer Letters, 2025 - Elsevier
Ovarian cancer (OC) accounts for the highest mortality rates among all gynecologic
malignancies. The high mortality of OC is often associated with delayed detection …

[HTML][HTML] The landscape of circRNAs in gliomas temozolomide resistance: Insights into molecular pathways

A Mafi, N Hedayati, S Kahkesh, S Khoshayand… - Non-coding RNA …, 2024 - Elsevier
As the deadliest type of primary brain tumor, gliomas represent a significant worldwide
health concern. Circular RNA (circRNA), a unique non-coding RNA molecule, seems to be …