Mechanistic insights into circRNA-mediated regulation of PI3K signaling pathway in glioma progression

A Mafi, SM Khoshnazar, A Shahpar, N Nabavi… - … -Research and Practice, 2024 - Elsevier
Abstract Circular RNAs (CircRNAs) are non-coding RNAs (ncRNAs) characterized by a
stable circular structure that regulates gene expression at both transcriptional and post …

Electrochemical biosensors for early diagnosis of glioblastoma

H Vatankhahan, F Esteki, MA Jabalameli, P Kiani… - Clinica Chimica …, 2024 - Elsevier
Glioblastoma (GBM) is a highly aggressive and life-threatening neurological malignancy of
predominant astrocyte origin. This type of neoplasm can develop in either the brain or the …

The role of miRNAs as biomarkers in breast cancer

T Baylie, M Kasaw, G Getie, M Jemal, H Ahmed… - Frontiers in …, 2024 - frontiersin.org
Breast cancer (BC) is the second most common cause of deaths reported in women
worldwide, and therefore there is a need to identify BC patients at an early stage as timely …

Circular RNAs and cervical cancer: friends or foes? A landscape on circRNA-mediated regulation of key signaling pathways involved in the onset and progression of …

E Heydarnia, Z Dorostgou, N Hedayati… - Cell Communication and …, 2024 - Springer
Cervical cancer (CC) is a common gynecologic malignancy, accounting for a significant
proportion of women death worldwide. Human papillomavirus (HPV) infection is one of the …

[HTML][HTML] The landscape of circRNAs in gliomas temozolomide resistance: Insights into molecular pathways

A Mafi, N Hedayati, S Kahkesh, S Khoshayand… - Non-coding RNA …, 2024 - Elsevier
As the deadliest type of primary brain tumor, gliomas represent a significant worldwide
health concern. Circular RNA (circRNA), a unique non-coding RNA molecule, seems to be …

[HTML][HTML] Flavonoids as modulators of miRNA expression in pancreatic cancer: Pathways, Mechanisms, And Therapeutic Potential

H Helen, MC Gunawan, P Halim, MR Dinata… - Biomedicine & …, 2024 - Elsevier
Pancreatic cancer (PC) is a complex malignancy, distinguished by its aggressive
characteristics and unfavorable prognosis. Recent developments in understanding the …

[HTML][HTML] Development and validation of a prognostic and drug sensitivity model for gastric cancer utilizing telomere-related genes

X Li, X Wang, F Yu, Z Li, D Chen, Y Qi, Z Lu, Y Liu… - Translational …, 2025 - Elsevier
Background Gastric cancer (GC) poses a major global health challenge because of its
unfavorable prognosis. Elevated telomerase activity has been linked to the rapid growth and …

Exosomal PSM-E inhibits macrophage M2 polarization to suppress prostate cancer metastasis through the RACK1 signaling axis

X Qin, R Niu, Y Tan, Y Huang, W Ren, W Zhou, H Wu… - Biomarker …, 2024 - Springer
Background It is well-established that understanding the mechanism of prostate cancer
(PCa)-associated metastasis is paramount for improving its prognosis. Metastasis is known …

[HTML][HTML] Ferroptosis contributes to the progression of female-specific neoplasms, from breast cancer to gynecological malignancies in a manner regulated by non …

K Hushmandi, DJ Klionsky, AR Aref, M Bonyadi… - Non-coding RNA …, 2024 - Elsevier
Ferroptosis, a recently identified type of non-apoptotic cell death, triggers the elimination of
cells in the presence of lipid peroxidation and in an iron-dependent manner. Indeed …

MicroRNA dysregulation and its impact on apoptosis-related signaling pathways in myelodysplastic syndrome

N Hedayati, MS Naeini, MMA Sahebfosoul… - … -Research and Practice, 2024 - Elsevier
Myelodysplastic syndrome (MDS) holds a unique position among blood cancers,
encompassing a spectrum of blood-related disorders marked by impaired maturation of …