[HTML][HTML] Current status of quantum chemical studies of cyclodextrin host–guest complexes

AH Mazurek, Ł Szeleszczuk - Molecules, 2022 - mdpi.com
This article aims to review the application of various quantum chemical methods (semi-
empirical, density functional theory (DFT), second order Møller–Plesset perturbation theory …

Computer‐aided drug design to explore cyclodextrin therapeutics and biomedical applications

A Abdolmaleki, F Ghasemi… - Chemical Biology & Drug …, 2017 - Wiley Online Library
Cyclodextrin (CD) is a subset of the macrocyclic structural class, which is an important class
of small organic agents that are useful functional excipients. They have wide range …

Synthesis and Characterization of an Inclusion Complex of dl-Aminoglutethimide with β-Cyclodextrin and Its Innovative Application in a Biological System …

S Ray, N Roy, BK Barman, P Karmakar, P Bomzan… - Acs Omega, 2022 - ACS Publications
Our present study intended to investigate the encapsulation of DL-AGT within the lipophilic
cavity of a β-CD molecule. The consequential inclusion system was characterized by UV …

Gastroretentive microsponge as a promising tool for prolonging the release of mitiglinide calcium in type-2 diabetes mellitus: optimization and pharmacokinetics study

DBED Mahmoud, MH Shukr, AN ElMeshad - AAPS PharmSciTech, 2018 - Springer
Diabetes mellitus is one of the leading causes of death due to the persistent hyperglycemia
that leads to potential complications. Lack of patients' adherence to their prescribed …

Physicochemical characterization and cyclodextrin complexation of the anticancer drug lapatinib

G Tóth, Á Jánoska, G Völgyi, ZI Szabó… - Journal of …, 2017 - Wiley Online Library
Lapatinib (LAP), the tyrosine kinase inhibitor drug with moderate bioavailability, was
characterized in terms of physicochemical properties: acid‐base characteristics, lipophilicity …

Synergistic Effect in the Ternary System of Citral Microemulsion Based on Self-Assembled Complex Surfactants

J Huang, Y Yang, T Li, H Yu, C Chen… - Industrial & …, 2024 - ACS Publications
Complex ternary supramolecular systems constituted by citral, surfactants, and cyclodextrins
were constructed in this paper. The composite emulsifier formed by Tween-80 and …

Gastroretentive cosolvent-based in situ gel as a promising approach for simultaneous extended delivery and enhanced bioavailability of mitiglinide calcium

DB Mahmoud, MH Shukr, AN ElMeshad - Journal of Pharmaceutical …, 2019 - Elsevier
Ion cross-linking in situ gels are novel liquid sustained-release drug delivery systems. These
systems are unsuitable for poorly water-soluble drugs such as the novel antidiabetic drug …

[HTML][HTML] Membrane cholesterol depletion in cortical neurons highlights altered NMDA receptor functionality in a mouse model of amyotrophic lateral sclerosis

A Antonini, S Caioli, L Saba, G Vindigni… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Abstract Amyotrophic Lateral Sclerosis (ALS) is a chronic neurodegenerative disease
affecting upper and lower motor neurons, with unknown aetiology. Lipid rafts, cholesterol …

Synthesis and characterization of an industrially significant ionic liquid and its inclusion complex with β-cyclodextrin and its soluble derivative for their advanced …

R Ghosh, N Roy, S Saha, S Das, BK Barman… - Chemical Physics …, 2021 - Elsevier
Thermochromic also solvatochromic ionic liquid surfactant was synthesized and
characterised. The surface activity, size and stability were estimated by surface tension, SEM …

A novel and simple dynamic coating capillary electrophoresis method for the chiral separation and quantification of mitiglinide enantiomers using hydroxyethyl …

KM Al Azzam - Die Pharmazie-An International Journal of …, 2022 - ingentaconnect.com
A capillary electrophoretic method for the chiral separation and quantification of mitiglinide
(MTG) enantiomers is described (less than 9.5 min) with resolution value Rs= 5.25 and with …