New progress in azole compounds as antimicrobial agents

HZ Zhang, LL Gan, H Wang… - Mini reviews in medicinal …, 2017 - ingentaconnect.com
The increasing incidence of microbial resistance and newly emerging pathogens have
become a serious challenge for public health. More and more efforts have been directed to …

A comprehensive review on steroidal bioconjugates as promising leads in drug discovery

R Bansal, A Suryan - ACS bio & med Chem Au, 2022 - ACS Publications
Ever increasing unmet medical requirements of the human race and the continuous fight for
survival against variety of diseases give birth to novel molecules through research. As …

An updated review on the synthesis and antibacterial activity of molecular hybrids and conjugates bearing imidazole moiety

R Rossi, M Ciofalo - Molecules, 2020 - mdpi.com
The rapid growth of serious infections caused by antibiotic resistant bacteria, especially the
nosocomial ESKAPE pathogens, has been acknowledged by Governments and scientists …

Pyridines and Imidazopyridines with medicinal significance

T LS Kishbaugh - Current Topics in Medicinal Chemistry, 2016 - ingentaconnect.com
Pyridine and pyridine-fused ring systems are ubiquitous in medicinal research and
demonstrate such diverse pharmacological benefits as anticonvulsant therapies, treatment …

Synthesis, characterization, and antioxidant properties of novel inulin derivatives with amino-pyridine group

Y Hu, J Zhang, C Yu, Q Li, F Dong, G Wang… - International journal of …, 2014 - Elsevier
A series of novel inulin derivatives were synthesized via reaction of chloracetyl inulin (CAIL)
with amino-pyridines, including 2-(2-amino-pyridyl) acetyl inulin chloride (2APAIL), 2-(3 …

[HTML][HTML] Steroid-triazole conjugates: A brief overview of synthesis and their application as anticancer agents

DS Agarwal, R Sakhuja, RM Beteck, LJ Legoabe - Steroids, 2023 - Elsevier
Steroids are biomolecules that play pivotal roles in various physiological and drug discovery
processes. Abundant research has been fuelled towards steroid-heterocycles conjugates …

[HTML][HTML] The Structure–Antiproliferative Activity Relationship of Pyridine Derivatives

AL Villa-Reyna, M Perez-Velazquez… - International Journal of …, 2024 - mdpi.com
Pyridine, a compound with a heterocyclic structure, is a key player in medicinal chemistry
and drug design. It is widely used as a framework for the design of biologically active …

Imidazole: an essential edifice for the identification of new lead compounds and drug development

N Shalmali, MR Ali, S Bawa - Mini reviews in medicinal …, 2018 - ingentaconnect.com
In recent years, a drastic rise has been observed in incidences of resistance, low efficacy
rates and toxicities to various drugs used in therapeutic application. Presence of imidazole …

Novel amino-pyridine functionalized chitosan quaternary ammonium derivatives: Design, synthesis, and antioxidant activity

Q Li, C Zhang, W Tan, G Gu, Z Guo - Molecules, 2017 - mdpi.com
Chemical modification of chitosan is increasingly studied for its potential of providing new
applications of chitosan. Here, a group of novel chitosan quaternary ammonium derivatives …

A review of pyridine and pyrimidine derivatives as anti-MRSA agents

A Kumar, AK Singh, S Thareja, P Kumar - Anti-Infective Agents, 2023 - ingentaconnect.com
Background: Methicillin-resistant Staphylococcus aureus (MRSA) is a Gram-positive strain
whose resistance against existing antibiotics is a significant concern for researchers across …