Physical exercise is of great significance for maintaining human health. Exercise can
provide varying degrees of benefits to cognitive function at all stages of life cycle. Currently …

Mitochondria are implicated in a wide range of functions apart from ATP generation, and,
therefore, constitute one of the most important organelles of cell. Since healthy mitochondria …

Background Age‐associated sarcopenia is characterized of progressed loss of skeletal
muscle power, mass, and function, which affects human physical activity and life quality …

Physical activity has been known as an essential element to promote human health for
centuries. Thus, exercise intervention is encouraged to battle against sedentary lifestyle …

Alzheimer's disease (AD) is the most prevalent form of dementia, characterized by the
presence of plaques of amyloid beta and Tau proteins. There is currently no permanent cure …

Introduction Obesity-induced bone loss affects the life quality of patients all over the world.
Irisin, one of the myokines, plays an essential role in bone and fat metabolism. Objective …

Background With the development of population aging worldwide, sarcopenia and knee
osteoarthritis (KOA), two age-related diseases, will continue to impose increasing medical …

With the increasingly severe situation of obesity and population aging, there is growing
concern about sarcopenia obesity (SO). SO refers to the coexistence of obesity and …

Irisin, a new exercise-mediated myokine, plays an important role in cardiovascular diseases
by regulating cell energy metabolism. The induction of mitochondrial dysfunction and …

Sarcopenic obesity, low muscle mass, and high body fat are growing health concerns in the
aging population. This review highlights the need for standardized criteria and explores …