Chromone: a valid scaffold in medicinal chemistry
Chromones are a group of naturally occurring compounds that are ubiquitous in nature,
especially in plants. The word chromone is derived from the Greek word chroma, meaning …
especially in plants. The word chromone is derived from the Greek word chroma, meaning …
Chromones as a privileged scaffold in drug discovery: A review
The chromone and its derivatives are the most important heterocyclic compounds, which is a
common and integral feature of a variety of natural products and medicinal agents. These …
common and integral feature of a variety of natural products and medicinal agents. These …
Cytotoxic activity of 3-(5-phenyl-3H-[1, 2, 4] dithiazol-3-yl) chromen-4-ones and 4-oxo-4H-chromene-3-carbothioic acid N-phenylamides
6/6, 7-Substituted-3-formylchromones (8a–g) were reacted with 2 equivalents
thiobenzamide (9) in refluxing toluene to furnish substituted-3-(5-phenyl-3H-[1, 2, 4] dithiazol …
thiobenzamide (9) in refluxing toluene to furnish substituted-3-(5-phenyl-3H-[1, 2, 4] dithiazol …
An update on natural occurrence and biological activity of chromones
The chemistry of chromones is very well known. This system is widely used in organic
chemistry as an intermediate compound for the synthesis of numerous hetrocycles. On the …
chemistry as an intermediate compound for the synthesis of numerous hetrocycles. On the …
One-pot synthesis of dihydropyrano [2, 3-c] chromenes via a three component coupling of aromatic aldehydes, malononitrile, and 3-hydroxycoumarin catalyzed by …
An efficient and green protocol for the synthesis of dihydropyrano [2, 3-c] chromene
derivatives by one-pot, three component coupling reaction of aromatic aldehyde …
derivatives by one-pot, three component coupling reaction of aromatic aldehyde …
Synthesis, structure–activity relationship of novel substituted 4H-chromen-1, 2, 3, 4-tetrahydropyrimidine-5-carboxylates as potential anti-mycobacterial and anticancer …
Abstract Series of 4H-chromen-1, 2, 3, 4-tetrahydropyrimidine-5-carboxylate derivatives 7a–
7zb, 8a–8d and 9a–9d were synthesized and screened for their in vitro anti-mycobacterial …
7zb, 8a–8d and 9a–9d were synthesized and screened for their in vitro anti-mycobacterial …
Design, Synthesis, Biological Evaluation, and Molecular Modeling of Novel 4H-Chromene Analogs as Potential Succinate Dehydrogenase Inhibitors
T Lu, Y Yan, T Zhang, G Zhang, T **ao… - Journal of Agricultural …, 2021 - ACS Publications
Thirty-one new 4 H-chromene derivatives were designed and synthesized. Their structures
were identified with IR, 1H NMR, 13C NMR, and HRMS. The crystal structure of compound …
were identified with IR, 1H NMR, 13C NMR, and HRMS. The crystal structure of compound …
Recyclizations of 3-formylchromones with binucleophiles
Chromones are widely recognized as an important class of biologically active compounds of
both natural and synthetic origin. 1 e8 The less known but very useful application of the …
both natural and synthetic origin. 1 e8 The less known but very useful application of the …
Highly efficient three-component, one-pot synthesis of dihydropyrano[3,2-c]chromene derivatives
HJ Wang, J Lu, ZH Zhang - Monatshefte für Chemie-Chemical Monthly, 2010 - Springer
An efficient and convenient method for synthesis of dihydropyrano [3, 2-c] chromene
derivatives by one-pot, three-component reaction of aldehydes, malononitrile, and 4 …
derivatives by one-pot, three-component reaction of aldehydes, malononitrile, and 4 …
Magnetically retrievable nano crystalline CuFe 2 O 4 catalyzed multi-component reaction: a facile and efficient synthesis of functionalized dihydropyrano [2, 3-c] …
K Pradhan, S Paul, AR Das - Catalysis Science & Technology, 2014 - pubs.rsc.org
CuFe2O4 magnetic nanoparticles were synthesized and recognized as an efficient catalyst
for the one-pot synthesis of dihydropyrano [2, 3-c] pyrazole, pyrano [3, 2-c] coumarin and 4H …
for the one-pot synthesis of dihydropyrano [2, 3-c] pyrazole, pyrano [3, 2-c] coumarin and 4H …