HOTAIR: a potential metastatic, drug-resistant and prognostic regulator of breast cancer
HOX transcript antisense intergenic RNA (HOTAIR) is an oncogenic non-coding RNA whose
expression is strongly correlated with the tumor grade and prognosis of a variety of …
expression is strongly correlated with the tumor grade and prognosis of a variety of …
HOTAIR: an oncogenic long non-coding RNA in human cancer
Q Tang, SS Hann - Cellular Physiology and Biochemistry, 2018 - karger.com
Abstract Long non-coding RNAs (LncRNAs) represent a novel class of noncoding RNAs that
are longer than 200 nucleotides without protein-coding potential and function as novel …
are longer than 200 nucleotides without protein-coding potential and function as novel …
[HTML][HTML] lncRNA and breast cancer: Progress from identifying mechanisms to challenges and opportunities of clinical treatment
H **, W Du, W Huang, J Yan, Q Tang, Y Chen… - … Therapy-Nucleic Acids, 2021 - cell.com
Breast cancer is a malignant tumor that has a high mortality rate and mostly occurs in
women. Although significant progress has been made in the implementation of personalized …
women. Although significant progress has been made in the implementation of personalized …
HOX transcript antisense RNA (HOTAIR) in cancer
X Qu, S Alsager, Y Zhuo, B Shan - Cancer letters, 2019 - Elsevier
Long noncoding RNAs (lncRNAs) have emerged as a new family of master regulators of
cancer. The lncRNA HOX transcript antisense RNA (HOTAIR) is a prime example of an …
cancer. The lncRNA HOX transcript antisense RNA (HOTAIR) is a prime example of an …
The lncRNA HOTAIR: a pleiotropic regulator of epithelial cell plasticity
L Amicone, A Marchetti, C Cicchini - Journal of Experimental & Clinical …, 2023 - Springer
The epithelial-to-mesenchymal transition (EMT) is a trans-differentiation process that
endows epithelial cells with mesenchymal properties, including motility and invasion …
endows epithelial cells with mesenchymal properties, including motility and invasion …
[HTML][HTML] Gene regulation by antisense transcription: A focus on neurological and cancer diseases
Advances in high-throughput sequencing over the past decades have led to the
identification of thousands of non-coding RNAs (ncRNAs), which play a major role in …
identification of thousands of non-coding RNAs (ncRNAs), which play a major role in …
[HTML][HTML] HOTAIR interacts with PRC2 complex regulating the regional preadipocyte transcriptome and human fat distribution
Mechanisms governing regional human adipose tissue (AT) development remain undefined.
Here, we show that the long non-coding RNA HOTAIR (HOX transcript antisense RNA) is …
Here, we show that the long non-coding RNA HOTAIR (HOX transcript antisense RNA) is …
The application of lncRNAs in cancer treatment and diagnosis
Y Zhang, L Tang - Recent patents on anti-cancer drug …, 2018 - ingentaconnect.com
Background: It is increasingly evident that lncRNAs have various biological functions playing
as essential regulators, getting involved in diverse cellular processes. Many of the lncRNAs …
as essential regulators, getting involved in diverse cellular processes. Many of the lncRNAs …
[HTML][HTML] Long non-coding RNAs in osteosarcoma
R Chen, G Wang, Y Zheng, Y Hua, Z Cai - Oncotarget, 2017 - ncbi.nlm.nih.gov
Long non-coding RNAs (lncRNAs) with more than 200 nuleotides, have been explored to
participate in various cancer types including osteosarcoma (OS), which is the most common …
participate in various cancer types including osteosarcoma (OS), which is the most common …
LncRNA HOTAIR in Tumor Microenvironment: What Role?
G Botti, G Scognamiglio, G Aquino, G Liguori… - International Journal of …, 2019 - mdpi.com
lncRNAs participate in many cellular processes, including regulation of gene expression at
the transcriptional and post-transcriptional levels. In addition, many lncRNAs can contribute …
the transcriptional and post-transcriptional levels. In addition, many lncRNAs can contribute …