Although an immense knowledge has accumulated concerning regulation of cholesterol
homeostasis in the body, this does not include the brain, where details are just emerging …

Without any exaggeration, cholesterol is one of the most important lipid species in eukaryotic
cells. Its effects on cellular membranes and functions range from purely mechanistic to …

We created nanometer-scale transmembrane channels in lipid bilayers by means of self-
assembled DNA-based nanostructures. Scaffolded DNA origami was used to create a stem …

Delivery of nucleic acids, such as mRNA, to immune cells has become a major focus in the
past decade with ionizable lipid nanoparticles (LNPs) emerging as a clinically-validated …

We have recently developed a novel computational methodology (termed RSF for Real-
Space Fluctuations) to quantify the bending rigidity and tilt modulus of lipid membranes from …

We present analysis of new configurational bias Monte Carlo and molecular dynamics
simulation data for bilayers of dipalmitoyl phosphatidyl choline and cholesterol for …

Simple Summary The success of semen preservation is vital for the use of artificial
reproductive technologies in sheep. However, reduced temperatures can cause significant …

It is well known that cholesterol modifies the physical properties of lipid bilayers. For
example, the much studied liquid-ordered L o phase contains rapidly diffusing lipids with …

The bilayer bending modulus (K c) is one of the most important physical constants
characterizing lipid membranes, but precisely measuring it is a challenge, both …

We present a unified continuum-level model for bilayer energetics that includes the effects of
bending, compression, lipid orientation (tilting relative to the monolayer surface normal), and …