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Brain cholesterol: long secret life behind a barrier
I Björkhem, S Meaney - Arteriosclerosis, thrombosis, and …, 2004 - ahajournals.org
Although an immense knowledge has accumulated concerning regulation of cholesterol
homeostasis in the body, this does not include the brain, where details are just emerging …
homeostasis in the body, this does not include the brain, where details are just emerging …
[HTML][HTML] Ordering effects of cholesterol and its analogues
Without any exaggeration, cholesterol is one of the most important lipid species in eukaryotic
cells. Its effects on cellular membranes and functions range from purely mechanistic to …
cells. Its effects on cellular membranes and functions range from purely mechanistic to …
Hydroxycholesterol substitution in ionizable lipid nanoparticles for mRNA delivery to T cells
Delivery of nucleic acids, such as mRNA, to immune cells has become a major focus in the
past decade with ionizable lipid nanoparticles (LNPs) emerging as a clinically-validated …
past decade with ionizable lipid nanoparticles (LNPs) emerging as a clinically-validated …
Synthetic lipid membrane channels formed by designed DNA nanostructures
We created nanometer-scale transmembrane channels in lipid bilayers by means of self-
assembled DNA-based nanostructures. Scaffolded DNA origami was used to create a stem …
assembled DNA-based nanostructures. Scaffolded DNA origami was used to create a stem …
[HTML][HTML] Progress in ATRP-derived materials for biomedical applications
The continuing wave of technological breakthroughs and advances is critical for engineering
well-defined materials, particularly biomaterials, with tailored microstructure and properties …
well-defined materials, particularly biomaterials, with tailored microstructure and properties …
Determination of bending rigidity and tilt modulus of lipid membranes from real-space fluctuation analysis of molecular dynamics simulations
We have recently developed a novel computational methodology (termed RSF for Real-
Space Fluctuations) to quantify the bending rigidity and tilt modulus of lipid membranes from …
Space Fluctuations) to quantify the bending rigidity and tilt modulus of lipid membranes from …
Cholesterol-induced modifications in lipid bilayers: a simulation study
SW Chiu, E Jakobsson, RJ Mashl, HL Scott - Biophysical journal, 2002 - cell.com
We present analysis of new configurational bias Monte Carlo and molecular dynamics
simulation data for bilayers of dipalmitoyl phosphatidyl choline and cholesterol for …
simulation data for bilayers of dipalmitoyl phosphatidyl choline and cholesterol for …
Cholesterol's location in lipid bilayers
It is well known that cholesterol modifies the physical properties of lipid bilayers. For
example, the much studied liquid-ordered L o phase contains rapidly diffusing lipids with …
example, the much studied liquid-ordered L o phase contains rapidly diffusing lipids with …
[HTML][HTML] Factors affecting the survival of ram spermatozoa during liquid storage and options for improvement
N Rizkallah, CG Chambers, SP de Graaf, JP Rickard - Animals, 2022 - mdpi.com
Simple Summary The success of semen preservation is vital for the use of artificial
reproductive technologies in sheep. However, reduced temperatures can cause significant …
reproductive technologies in sheep. However, reduced temperatures can cause significant …
The effect of variations in phospholipid and sterol structure on the nature of lipid–sterol interactions in lipid bilayer model membranes
DA Mannock, RNAH Lewis, TPW McMullen… - Chemistry and physics …, 2010 - Elsevier
This review deals with the effect of variations in phospholipid and sterol structure on the
nature and magnitude of lipid-sterol interactions in lipid bilayer model membranes. The first …
nature and magnitude of lipid-sterol interactions in lipid bilayer model membranes. The first …