Brain cholesterol: long secret life behind a barrier

I Björkhem, S Meaney - Arteriosclerosis, thrombosis, and …, 2004 - ahajournals.org
Although an immense knowledge has accumulated concerning regulation of cholesterol
homeostasis in the body, this does not include the brain, where details are just emerging …

[HTML][HTML] Ordering effects of cholesterol and its analogues

T Róg, M Pasenkiewicz-Gierula, I Vattulainen… - … et Biophysica Acta (BBA …, 2009 - Elsevier
Without any exaggeration, cholesterol is one of the most important lipid species in eukaryotic
cells. Its effects on cellular membranes and functions range from purely mechanistic to …

Hydroxycholesterol substitution in ionizable lipid nanoparticles for mRNA delivery to T cells

SK Patel, MM Billingsley, C Frazee, X Han… - Journal of Controlled …, 2022 - Elsevier
Delivery of nucleic acids, such as mRNA, to immune cells has become a major focus in the
past decade with ionizable lipid nanoparticles (LNPs) emerging as a clinically-validated …

Synthetic lipid membrane channels formed by designed DNA nanostructures

M Langecker, V Arnaut, TG Martin, J List, S Renner… - Science, 2012 - science.org
We created nanometer-scale transmembrane channels in lipid bilayers by means of self-
assembled DNA-based nanostructures. Scaffolded DNA origami was used to create a stem …

[HTML][HTML] Progress in ATRP-derived materials for biomedical applications

MK Yazdi, P Zarrintaj, MR Saeb, M Mozafari… - Progress in Materials …, 2024 - Elsevier
The continuing wave of technological breakthroughs and advances is critical for engineering
well-defined materials, particularly biomaterials, with tailored microstructure and properties …

Determination of bending rigidity and tilt modulus of lipid membranes from real-space fluctuation analysis of molecular dynamics simulations

M Doktorova, D Harries, G Khelashvili - Physical Chemistry Chemical …, 2017 - pubs.rsc.org
We have recently developed a novel computational methodology (termed RSF for Real-
Space Fluctuations) to quantify the bending rigidity and tilt modulus of lipid membranes from …

Cholesterol-induced modifications in lipid bilayers: a simulation study

SW Chiu, E Jakobsson, RJ Mashl, HL Scott - Biophysical journal, 2002 - cell.com
We present analysis of new configurational bias Monte Carlo and molecular dynamics
simulation data for bilayers of dipalmitoyl phosphatidyl choline and cholesterol for …

Cholesterol's location in lipid bilayers

D Marquardt, N Kučerka, SR Wassall… - Chemistry and Physics …, 2016 - Elsevier
It is well known that cholesterol modifies the physical properties of lipid bilayers. For
example, the much studied liquid-ordered L o phase contains rapidly diffusing lipids with …

[HTML][HTML] Factors affecting the survival of ram spermatozoa during liquid storage and options for improvement

N Rizkallah, CG Chambers, SP de Graaf, JP Rickard - Animals, 2022 - mdpi.com
Simple Summary The success of semen preservation is vital for the use of artificial
reproductive technologies in sheep. However, reduced temperatures can cause significant …

The effect of variations in phospholipid and sterol structure on the nature of lipid–sterol interactions in lipid bilayer model membranes

DA Mannock, RNAH Lewis, TPW McMullen… - Chemistry and physics …, 2010 - Elsevier
This review deals with the effect of variations in phospholipid and sterol structure on the
nature and magnitude of lipid-sterol interactions in lipid bilayer model membranes. The first …