Mycolic acids are major and specific lipid components of the mycobacterial cell envelope
and are essential for the survival of members of the genus Mycobacterium that contains the …

Mycobacterium tuberculosis (Mtb), the etiological agent of tuberculosis (TB), is recognized
as a global health emergency as promoted by the World Health Organization. Over 1 million …

Mycobacterium tuberculosis (Mtb) lipids are indelibly imprinted in just about every key
aspect of tuberculosis (TB) basic and translational research. Although the interest in these …

Tuberculosis (TB) remains the second most common cause of death due to a single
infectious agent. The cell envelope of Mycobacterium tuberculosis (Mtb), the causative agent …

Mycobacterium tuberculosis, the bacterium responsible for tuberculosis, is the global
leading cause of mortality from an infectious agent. Part of this success relies on the unique …

The increasing prevalence of drug-resistant tuberculosis highlights the need for identifying
new antitubercular drugs that can treat these infections. The antigen 85 (Ag85) complex has …

Most of the newly discovered compounds showing promise for the treatment of TB, notably
multidrug-resistant TB, inhibit aspects of Mycobacterium tuberculosis cell envelope …

Mycolic acids are the major lipid components of the unique mycobacterial cell wall
responsible for the protection of the tuberculosis bacilli from many outside threats. Mycolic …

The spread of antibiotic resistance is a major challenge for the treatment of Mycobacterium
tuberculosis infections. In addition, the efficacy of drugs is often limited by the restricted …

The disaccharide trehalose is essential for viability of Mycobacterium tuberculosis, which
synthesizes trehalose de novo but can also utilize exogenous trehalose. The mycobacterial …