The astounding world of glycans from giant viruses
Viruses are a heterogeneous ensemble of entities, all sharing the need for a suitable host to
replicate. They are extremely diverse, varying in morphology, size, nature, and complexity of …
replicate. They are extremely diverse, varying in morphology, size, nature, and complexity of …
The flagellum attachment zone:'the cellular ruler'of trypanosome morphology
JD Sunter, K Gull - Trends in parasitology, 2016 - cell.com
A defining feature of Trypanosoma brucei cell shape is the lateral attachment of the
flagellum to the cell body, mediated by the flagellum attachment zone (FAZ). The FAZ is a …
flagellum to the cell body, mediated by the flagellum attachment zone (FAZ). The FAZ is a …
New chemotherapy regimens and biomarkers for Chagas disease: the rationale and design of the TESEO study, an open-label, randomised, prospective, phase-2 …
Introduction Chagas disease (CD) affects~ 7 million people worldwide. Benznidazole (BZN)
and nifurtimox (NFX) are the only approved drugs for CD chemotherapy. Although both …
and nifurtimox (NFX) are the only approved drugs for CD chemotherapy. Although both …
[HTML][HTML] Glycomics, glycoproteomics, and glycogenomics: an inter-taxa evolutionary perspective
CM West, D Malzl, A Hykollari, IBH Wilson - Molecular & Cellular …, 2021 - Elsevier
Glycosylation is a highly diverse set of co-and posttranslational modifications of proteins. For
mammalian glycoproteins, glycosylation is often site-, tissue-, and species-specific and …
mammalian glycoproteins, glycosylation is often site-, tissue-, and species-specific and …
[HTML][HTML] Rhamnose-containing compounds: biosynthesis and applications
S Li, F Chen, Y Li, L Wang, H Li, G Gu, E Li - Molecules, 2022 - mdpi.com
Rhamnose-associated molecules are attracting attention because they are present in
bacteria but not mammals, making them potentially useful as antibacterial agents …
bacteria but not mammals, making them potentially useful as antibacterial agents …
Structure of N-linked oligosaccharides attached to chlorovirus PBCV-1 major capsid protein reveals unusual class of complex N-glycans
The major capsid protein Vp54 from the prototype chlorovirus Paramecium bursaria
chlorella virus 1 (PBCV-1) contains four Asn-linked glycans. The structure of the four N …
chlorella virus 1 (PBCV-1) contains four Asn-linked glycans. The structure of the four N …
[HTML][HTML] The autonomous glycosylation of large DNA viruses
F Piacente, M Gaglianone, ME Laugieri… - International Journal of …, 2015 - mdpi.com
Glycosylation of surface molecules is a key feature of several eukaryotic viruses, which use
the host endoplasmic reticulum/Golgi apparatus to add carbohydrates to their nascent …
the host endoplasmic reticulum/Golgi apparatus to add carbohydrates to their nascent …
Anionic and zwitterionic moieties as widespread glycan modifications in non-vertebrates
K Paschinger, IBH Wilson - Glycoconjugate journal, 2020 - Springer
Glycan structures in non-vertebrates are highly variable; it can be assumed that this is a
product of evolution and speciation, not that it is just a random event. However, in animals …
product of evolution and speciation, not that it is just a random event. However, in animals …
The α-Galactosyl Carbohydrate Epitope in Pathogenic Protozoa
RM De Lederkremer, ME Giorgi… - ACS Infectious …, 2022 - ACS Publications
The α-gal epitope, which refers to the carbohydrate α-d-Gal p-(1→ 3)-β-d-Gal p-(1→ 4)-d-
GlcNAc-R, was first described in the glycoconjugates of mammals other than humans …
GlcNAc-R, was first described in the glycoconjugates of mammals other than humans …
Analysis of zwitterionic and anionic N-linked glycans from invertebrates and protists by mass spectrometry
K Paschinger, IBH Wilson - Glycoconjugate journal, 2016 - Springer
Glycomic analyses over the years have revealed that non-vertebrate eukaryotes express
oligosaccharides with inorganic and zwitterionic modifications which are either occurring in …
oligosaccharides with inorganic and zwitterionic modifications which are either occurring in …