The efficacy of psychotherapies and pharmacotherapies for mental disorders in adults: an umbrella review and meta‐analytic evaluation of recent meta‐analyses

F Leichsenring, C Steinert, S Rabung… - World …, 2022‏ - Wiley Online Library
Mental disorders represent a worldwide public health concern. Psychotherapies and
pharmacotherapies are recommended as first line treatments. However, evidence has …

Circadian mechanisms in medicine

R Allada, J Bass - New England Journal of Medicine, 2021‏ - Mass Medical Soc
Circadian Mechanisms in Medicine Molecular insights into diurnal variations in human
physiology and behavior are extending our understanding of a wide range of disease …

Increased risk for COVID‐19 breakthrough infection in fully vaccinated patients with substance use disorders in the United States between December 2020 and …

L Wang, QQ Wang, PB Davis, ND Volkow… - World …, 2022‏ - Wiley Online Library
Individuals with substance use disorders (SUDs) are at increased risk for COVID‐19
infection and for adverse outcomes of the infection. Though vaccines are highly effective …

[HTML][HTML] The chronic mild stress (CMS) model of depression: History, evaluation and usage

P Willner - Neurobiology of stress, 2017‏ - Elsevier
Now 30 years old, the chronic mild stress (CMS) model of depression has been used in>
1300 published studies, with a year-on-year increase rising to> 200 papers in 2015. Data …

Animal models of addiction

R Spanagel - Dialogues in clinical neuroscience, 2017‏ - Taylor & Francis
In recent years, animal models in psychiatric research have been criticized for their limited
translational value to the clinical situation. Failures in clinical trials have thus often been …

Pharmacological and non-pharmacological treatments for major depressive disorder: review of systematic reviews

G Gartlehner, G Wagner, N Matyas, V Titscher… - BMJ open, 2017‏ - bmjopen.bmj.com
Objectives This study aims to summarise the evidence on more than 140 pharmacological
and non-pharmacological treatment options for major depressive disorder (MDD) and to …

Evidence-based guidelines for treating depressive disorders with antidepressants: a revision of the 2008 British Association for Psychopharmacology guidelines

A Cleare, CM Pariante, AH Young… - Journal of …, 2015‏ - journals.sagepub.com
A revision of the 2008 British Association for Psychopharmacology evidence-based
guidelines for treating depressive disorders with antidepressants was undertaken in order to …

Comparative efficacy and tolerability of pharmacological treatments for the treatment of acute bipolar depression: a systematic review and network meta-analysis

A Bahji, D Ermacora, C Stephenson… - Journal of affective …, 2020‏ - Elsevier
Objective We investigated the comparative efficacy and tolerability of pharmacological
treatment strategies for the treatment of acute bipolar depression. Data sources A systematic …

The overlap between anxiety, depression, and obsessive-compulsive disorder

GM Goodwin - Dialogues in clinical neuroscience, 2015‏ - Taylor & Francis
The anxiety disorders include generalized anxiety disorder, specific phobia, social phobia,
agoraphobia, and panic disorder. In addition to the specific symptoms of these disorders …

Circadian depression: a mood disorder phenotype

JS Carpenter, JJ Crouse, EM Scott, SL Naismith… - Neuroscience & …, 2021‏ - Elsevier
Major mood syndromes are among the most common and disabling mental disorders.
However, a lack of clear delineation of their underlying pathophysiological mechanisms is a …