• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

In the last three decades, ablation of atrial fibrillation (AF) has become an evidence-based
safe and efficacious treatment for managing the most common cardiac arrhythmia. In 2007 …

Abstract Aim The “2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management
of Patients With Atrial Fibrillation” provides recommendations to guide clinicians in the …

Importance Ablation of persistent atrial fibrillation (AF) remains a challenge. Left atrial
fibrosis plays an important role in the pathophysiology of AF and has been associated with …

MicroRNAs (miRNAs) are small regulatory molecules post-transcriptionally suppressing
mRNA activity. Many miRNAs in various organisms have been cloned but many unknown …

Accompanying the aging of populations worldwide, and increased survival with chronic
diseases, the incidence and prevalence of atrial fibrillation (AF) are rising, justifying the term …

Despite marked progress in the management of atrial fibrillation (AF), detecting AF remains
difficult and AF-related complications cause unacceptable morbidity and mortality even on …

Importance Obesity increases the incidence and mortality from some types of cancer, but it
remains uncertain whether intentional weight loss can decrease this risk. Objective To …

Background: Even on optimal therapy, many patients with heart failure and atrial fibrillation
experience cardiovascular complications. Additional treatments are needed to reduce these …

Atrial fibrillation (AF) is a highly prevalent arrhythmia, with substantial associated morbidity
and mortality. There have been significant management advances over the past 2 decades …