[HTML][HTML] Cognitive impairment in people with epilepsy
A Novak, K Vizjak, M Rakusa - Journal of Clinical Medicine, 2022 - mdpi.com
People with epilepsy frequently have cognitive impairment. The majority of cognitive
problems is influenced by a variety of interlinked factors, including the early onset of …
problems is influenced by a variety of interlinked factors, including the early onset of …
Hippocampal sharp wave‐ripple: A cognitive biomarker for episodic memory and planning
G Buzsáki - Hippocampus, 2015 - Wiley Online Library
Sharp wave ripples (SPW‐Rs) represent the most synchronous population pattern in the
mammalian brain. Their excitatory output affects a wide area of the cortex and several …
mammalian brain. Their excitatory output affects a wide area of the cortex and several …
Cognitive impairment in epilepsy: the role of network abnormalities
GL Holmes - Epileptic Disorders, 2015 - Wiley Online Library
The challenges to individuals with epilepsy extend far beyond the seizures. Co‐morbidities
in epilepsy are very common and are often more problematic to individuals than the seizures …
in epilepsy are very common and are often more problematic to individuals than the seizures …
Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model
In light of the rising prevalence of Alzheimer's disease (AD), new strategies to prevent, halt,
and reverse this condition are needed urgently. Perturbations of brain network activity are …
and reverse this condition are needed urgently. Perturbations of brain network activity are …
Interictal epileptiform discharges induce hippocampal–cortical coupling in temporal lobe epilepsy
Interactions between the hippocampus and the cortex are critical for memory. Interictal
epileptiform discharges (IEDs) identify epileptic brain regions and can impair memory, but …
epileptiform discharges (IEDs) identify epileptic brain regions and can impair memory, but …
Cognitive and neurodevelopmental comorbidities in paediatric epilepsy
KC Nickels, MJ Zaccariello, LD Hamiwka… - Nature Reviews …, 2016 - nature.com
Cognitive and behavioural comorbidities are often seen in children with epilepsy, and are
more common and severe in refractory epilepsy. These comorbidities are associated with …
more common and severe in refractory epilepsy. These comorbidities are associated with …
Hippocampal interictal epileptiform activity disrupts cognition in humans
Objective: We investigated whether interictal epileptiform discharges (IED) in the human
hippocampus are related to impairment of specific memory processes, and which …
hippocampus are related to impairment of specific memory processes, and which …
Histamine H3 receptor as a potential target for cognitive symptoms in neuropsychiatric diseases
The potential contributions of the brain histaminergic system in neurodegenerative diseases,
and the possiblity of histamine-targeting treatments is attracting considerable interests. The …
and the possiblity of histamine-targeting treatments is attracting considerable interests. The …
Seizures and epilepsy in Alzheimer's disease
Many studies have shown that patients with Alzheimer's disease (AD) are at increased risk
for develo** seizures and epilepsy. However, reported prevalence and incidence of …
for develo** seizures and epilepsy. However, reported prevalence and incidence of …
Interictal epileptiform activity outside the seizure onset zone impacts cognition
Abstract See Kleen and Kirsch (doi: 10.1093/awx178) for a scientific commentary on this
article. Cognitive deficits are common among epilepsy patients. In these patients, interictal …
article. Cognitive deficits are common among epilepsy patients. In these patients, interictal …