Targeting immunogenic cancer cell death by photodynamic therapy: past, present and future

R Alzeibak, TA Mishchenko… - Journal for …, 2021 - pmc.ncbi.nlm.nih.gov
The past decade has witnessed major breakthroughs in cancer immunotherapy. This
development has been largely motivated by cancer cell evasion of immunological control …

[HTML][HTML] Medical gas plasma technology: Roadmap on cancer treatment and immunotherapy

S Bekeschus - Redox biology, 2023 - Elsevier
Despite continuous therapeutic progress, cancer remains an often fatal disease. In the early
2010s, first evidence in rodent models suggested promising antitumor action of gas plasma …

Vaccination with early ferroptotic cancer cells induces efficient antitumor immunity

I Efimova, E Catanzaro… - Journal for …, 2020 - pmc.ncbi.nlm.nih.gov
Background Immunotherapy represents the future of clinical cancer treatment. The type of
cancer cell death determines the antitumor immune response and thereby contributes to the …

The function and mechanism of ferroptosis in cancer

Y Wang, Z Wei, K Pan, J Li, Q Chen - Apoptosis, 2020 - Springer
Ferroptosis is a newly defined form of regulated cell death (RCD) characterized by iron
overload, lipid reactive oxygen species (ROS) accumulation, and lipid peroxidation, which is …

Immunogenic ferroptosis and where to find it?

R Demuynck, I Efimova, F Naessens… - … for immunotherapy of …, 2021 - pmc.ncbi.nlm.nih.gov
Ferroptosis is a recently discovered form of regulated cell death that is morphologically,
genetically, and biochemically distinct from apoptosis and necroptosis, and its potential use …

Immunogenic cell death and role of nanomaterials serving as therapeutic vaccine for personalized cancer immunotherapy

E Catanzaro, O Feron, AG Skirtach… - Frontiers in …, 2022 - frontiersin.org
Immunogenic cell death (ICD) is a rapidly growing research area representing one of the
emerging therapeutic strategies of cancer immunotherapy. ICD is an umbrella term covering …

Novel porphyrazine-based photodynamic anti-cancer therapy induces immunogenic cell death

VD Turubanova, TA Mishchenko, IV Balalaeva… - Scientific Reports, 2021 - nature.com
The immunogenicity of dying cancer cells determines the efficacy of anti-cancer therapy.
Photodynamic therapy (PDT) can induce immunogenic cell death (ICD), which is …

AFM analysis enables differentiation between apoptosis, necroptosis, and ferroptosis in murine cancer cells

L Van der Meeren, J Verduijn, DV Krysko, AG Skirtach - Iscience, 2020 - cell.com
Regulated cell death (RCD) has a fundamental role in development, pathology, and tissue
homeostasis. In order to understand the RCD mechanisms, it is essential to follow these …

Curcumin suppresses cell proliferation and triggers apoptosis in vemurafenib‐resistant melanoma cells by downregulating the EGFR signaling pathway

YJ Chiu, JS Yang, FJ Tsai, HY Chiu… - Environmental …, 2022 - Wiley Online Library
Melanoma is a malignant tumor with aggressive behavior. Vemurafenib, a BRAF inhibitor, is
clinically used in melanoma, but resistance to melanoma cytotoxic therapies is associated …

Loss of Myo19 increases metastasis by enhancing microenvironmental ROS gradient and chemotaxis

X Ren, P Shi, J Su, T Wei, J Li, Y Hu, C Wu - EMBO reports, 2024 - embopress.org
Tumor metastasis involves cells migrating directionally in response to external chemical
signals. Reactive oxygen species (ROS) in the form of H2O2 has been demonstrated as a …