Retinoids in embryonal development

SA Ross, PJ McCaffery, UC Drager… - Physiological …, 2000 - journals.physiology.org
The key role of vitamin A in embryonal development is reviewed. Special emphasis is given
to the physiological action of retinoids, as evident from the retinoid ligand knockout models …

Cytosolic retinoid dehydrogenases govern ubiquitous metabolism of retinol to retinaldehyde followed by tissue-specific metabolism to retinoic acid

G Duester, FA Mic, A Molotkov - Chemico-biological interactions, 2003 - Elsevier
The ability of vitamin A (retinol) to control growth and development depends upon tissue-
specific metabolism of retinol to retinoic acid (RA). RA then functions as a ligand for retinoid …

[BOOK][B] Handbook of vitamins

J Zempleni, JW Suttie, JF Gregory III, PJ Stover - 2013 - books.google.com
Within the last few years, knowledge about vitamins has increased dramatically. This new
edition of a bestseller presents comprehensive summaries that analyze the chemical …

Retinoids in chemoprevention and differentiation therapy

LA Hansen, CC Sigman, F Andreola, SA Ross… - …, 2000 - academic.oup.com
Retinoids are essential for the maintenance of epithelial differentiation. As such, they play a
fundamental role in chemoprevention of epithelial carcinogenesis and in differentiation …

Vitamin a

AC Ross - Bioactive compounds and cancer, 2010 - Springer
Key Points 1. Retinoids are one of the most effective classes of agents for promoting cell
differentiation, and therefore are of strong interest for cancer prevention and cancer therapy …

[BOOK][B] Handbook of vitamins

RB Rucker, J Zempleni, JW Suttie, DB McCormick - 2007 - taylorfrancis.com
Thoroughly revised and updated, Handbook of Vitamins highlights the recent research in
vitamins and gene expression, vitamin-dependent genes, and vitamin effect on DNA …

[PDF][PDF] Vitamin A: nutritional aspects of retinoids and carotenoids

AC Ross, EH Harrison - Handbook of Vitamins, 4th Edition, USA …, 2007 - drhazhan.com
Vitamin A (retinol) is an essential micronutrient for all vertebrates. It is required for normal
vision, reproduction, embryonic development, cell and tissue differentiation, and immune …

Retinoic acid binding properties of the lipocalin member β-lactoglobulin studied by circular dichroism, electronic absorption spectroscopy and molecular modeling …

F Zsila, Z Bikádi, M Simonyi - Biochemical pharmacology, 2002 - Elsevier
Interaction between the Vitamin A derivative all-trans retinoic acid and the lipocalin member
bovine β-lactoglobulin (BLG) was studied by circular dichroism (CD) and electronic …

Inhaled Isotretinoin (13-cis Retinoic Acid) Is an Effective Lung Cancer Chemopreventive Agent in A/J Mice at Low doses: A Pilot Study

AR Dahl, IM Grossi, DP Houchens, LJ Scovell… - Clinical Cancer …, 2000 - AACR
In previously treated head-and-neck cancer patients, po administered isotretinoin (13-cis
retinoic acid) reduced the occurrence of second aerodigestive tumors, including lung …

Fatty acid Δ5-desaturase mRNA is regulated by dietary vitamin A and exogenous retinoic acid in liver of adult rats

R Zolfaghari, CJ Cifelli, MD Banta, AC Ross - Archives of Biochemistry and …, 2001 - Elsevier
Δ5-Desaturase (D5D) catalyzes the Δ5, 6 desaturation of dietary essential fatty acids of the n-
6 and n-3 series. By subtraction hybridization of vitamin A (VA)-deficient and control rat liver …