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Mendelian randomization for cardiovascular diseases: principles and applications
Large-scale genome-wide association studies conducted over the last decade have
uncovered numerous genetic variants associated with cardiometabolic traits and risk factors …
uncovered numerous genetic variants associated with cardiometabolic traits and risk factors …
Molecular aspects of fructose metabolism and metabolic disease
Excessive sugar consumption is increasingly considered as a contributor to the emerging
epidemics of obesity and the associated cardiometabolic disease. Sugar is added to the diet …
epidemics of obesity and the associated cardiometabolic disease. Sugar is added to the diet …
Coffee, caffeine, and health
Coffee, Caffeine, and Health In many countries, a large majority of adults consume caffeine
daily. This review summarizes the evidence about the varied physiological effects of caffeine …
daily. This review summarizes the evidence about the varied physiological effects of caffeine …
Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration
Vitamin D deficiency is a candidate risk factor for a range of adverse health outcomes. In a
genome-wide association study of 25 hydroxyvitamin D (25OHD) concentration in 417,580 …
genome-wide association study of 25 hydroxyvitamin D (25OHD) concentration in 417,580 …
Interindividual differences in caffeine metabolism and factors driving caffeine consumption
A Nehlig - Pharmacological reviews, 2018 - Elsevier
Most individuals adjust their caffeine intake according to the objective and subjective effects
induced by the methylxanthine. However, to reach the desired effects, the quantity of …
induced by the methylxanthine. However, to reach the desired effects, the quantity of …
Acute effects of coffee consumption on health among ambulatory adults
Background Coffee is one of the most commonly consumed beverages in the world, but the
acute health effects of coffee consumption remain uncertain. Methods We conducted a …
acute health effects of coffee consumption remain uncertain. Methods We conducted a …
International society of sports nutrition position stand: caffeine and exercise performance
NS Guest, TA VanDusseldorp, MT Nelson… - Journal of the …, 2021 - Taylor & Francis
Following critical evaluation of the available literature to date, The International Society of
Sports Nutrition (ISSN) position regarding caffeine intake is as follows: Supplementation with …
Sports Nutrition (ISSN) position regarding caffeine intake is as follows: Supplementation with …
Biomarkers of nutrition and health: new tools for new approaches
A main challenge in nutritional studies is the valid and reliable assessment of food intake, as
well as its effects on the body. Generally, food intake measurement is based on self-reported …
well as its effects on the body. Generally, food intake measurement is based on self-reported …
Implementing MR‐PRESSO and GCTA‐GSMR for pleiotropy assessment in Mendelian randomization studies from a practitioner's perspective
With the advent of very large scale genome‐wide association studies (GWASs), the promise
of Mendelian randomization (MR) has begun to be fulfilled. However, whilst GWASs have …
of Mendelian randomization (MR) has begun to be fulfilled. However, whilst GWASs have …
Modifiable pathways in Alzheimer's disease: Mendelian randomisation analysis
Objective To determine which potentially modifiable risk factors, including socioeconomic,
lifestyle/dietary, cardiometabolic, and inflammatory factors, are associated with Alzheimer's …
lifestyle/dietary, cardiometabolic, and inflammatory factors, are associated with Alzheimer's …