In pugilistic parlance, the one-two punch is a devastating combination of blows, with the first
punch setting the stage and the second delivering the knock-out. This analogy can be …

The WW domain‐containing oxidoreductase (WWOX) spans one of the most active common
fragile sites (CFSs) involved in cancer, FRA16D. WWOX encodes a 46‐kDa protein that …

MicroRNAs (miRNAs) are small, noncoding RNAs that regulate expression of many genes.
Recent studies suggest roles of miRNAs in carcinogenesis. We and others have shown that …

The WW domain-containing oxidoreductase (WWOX) spans the second most common
fragile site of the human genome, FRA16D, located at 16q23, and its expression is altered in …

Determining the mathematical dynamics and associated parameter values that should be
used to accurately reflect tumor growth continues to be of interest to mathematical modelers …

Head and neck squamous cell carcinoma (HNSCC) is a prevalent disease worldwide, and
the survival of HNSCC has not improved significantly over the last few decades. MicroRNAs …

Enhancer of zeste homolog 2 (EZH2) has been shown to be overexpressed in
hepatocellular (HCC). We investigated the potential role of EZH2 in HCC tumorigenesis and …

We performed fluorescent in situ hybridization (FISH) for 16q23 abnormalities in 861
patients with newly diagnosed multiple myeloma and identified deletion of 16q [del (16q)] in …

Background Brain metastasis (BM) is associated with poor prognosis in patients with non-
small cell lung cancer (NSCLC). Recent studies demonstrated that microRNA-330-3p (miR …

Despite decades of efforts, non-small-cell lung cancer (NSCLC) remains the leading cause
of cancer mortality globally primarily due to the challenge in early detection of the cancer …