[HTML][HTML] Biosafety of mesoporous silica nanoparticles; towards clinical translation

A Lérida-Viso, A Estepa-Fernández… - Advanced Drug Delivery …, 2023 - Elsevier
Mesoporous silica nanoparticles (MSNs) have attracted the attention of chemists, who have
developed numerous systems for the encapsulation of a plethora of molecules, allowing the …

Frontiers in the treatment of glioblastoma: Past, present and emerging

TI Janjua, P Rewatkar, A Ahmed-Cox, I Saeed… - Advanced drug delivery …, 2021 - Elsevier
Glioblastoma (GBM) is one of the most aggressive cancers of the brain. Despite extensive
research over the last several decades, the survival rates for GBM have not improved and …

Nanoparticles‐induced potential toxicity on human health: applications, toxicity mechanisms, and evaluation models

L Xuan, Z Ju, M Skonieczna, PK Zhou, R Huang - MedComm, 2023 - Wiley Online Library
Nanoparticles (NPs) have become one of the most popular objects of scientific study during
the past decades. However, despite wealth of study reports, still there is a gap, particularly in …

Mesoporous silica nanoparticles for pulmonary drug delivery

A Garcia-Fernandez, F Sancenon… - Advanced Drug Delivery …, 2021 - Elsevier
Over the last years, respiratory diseases represent a clinical concern, being included among
the leading causes of death in the world due to the lack of effective lung therapies, mainly …

Current trends in smart mesoporous silica-based nanovehicles for photoactivated cancer therapy

K Wang, J Lu, J Li, Y Gao, Y Mao, Q Zhao… - Journal of Controlled …, 2021 - Elsevier
Photoactivated therapeutic strategies (photothermal therapy and photodynamic therapy),
due to the adjusted therapeutic area, time and light dosage, have prevailed for the fight …

[HTML][HTML] A review on the latest developments of mesoporous silica nanoparticles as a promising platform for diagnosis and treatment of cancer

F Ahmadi, A Sodagar-Taleghani… - International Journal of …, 2022 - Elsevier
Cancer is the second cause of human mortality after cardiovascular disease around the
globe. Conventional cancer therapies are chemotherapy, radiation, and surgery. In fact, due …

Anionic nanoplastic exposure induces endothelial leakiness

W Wei, Y Li, M Lee, N Andrikopoulos, S Lin… - Nature …, 2022 - nature.com
The global-scale production of plastics has been instrumental in advancing modern society,
while the rising accumulation of plastics in landfills, oceans, and anything in between has …

Lipid-coated MCM-41 mesoporous silica nanoparticles loaded with berberine improved inhibition of acetylcholine esterase and amyloid formation

AK Singh, SS Singh, AS Rathore… - ACS Biomaterials …, 2021 - ACS Publications
Selective permeability of the blood–brain barrier limits effective treatment of
neurodegenerative disorders. In the present study, brain-targeted lipid-coated mesoporous …

Mechanisms of immune response to inorganic nanoparticles and their degradation products

R Mohammapdour, H Ghandehari - Advanced drug delivery reviews, 2022 - Elsevier
Careful assessment of the biological fate and immune response of inorganic nanoparticles
is crucial for use of such carriers in drug delivery and other biomedical applications. Many …

Adverse effects of amorphous silica nanoparticles: focus on human cardiovascular health

C Guo, Y Liu, Y Li - Journal of Hazardous Materials, 2021 - Elsevier
Amorphous silica nanoparticle (SiNPs) has tremendous potential for a host of applications,
while its mass production, broad application and environmental release inevitably increase …