Label‐free single cell proteomics utilizing ultrafast LC and MS instrumentation: A valuable complementary technique to multiplexing
M Matzinger, RL Mayer, K Mechtler - Proteomics, 2023 - Wiley Online Library
The ability to map a proteomic fingerprint to transcriptomic data would master the
understanding of how gene expression translates into actual phenotype. In contrast to …
understanding of how gene expression translates into actual phenotype. In contrast to …
Single-cell omics: experimental workflow, data analyses and applications
Cells are the fundamental units of biological systems and exhibit unique development
trajectories and molecular features. Our exploration of how the genomes orchestrate the …
trajectories and molecular features. Our exploration of how the genomes orchestrate the …
Single-cell RNA sequencing combined with single-cell proteomics identifies the metabolic adaptation of islet cell subpopulations to high-fat diet in mice
Q Fu, H Jiang, Y Qian, H Lv, H Dai, Y Zhou, Y Chen… - Diabetologia, 2023 - Springer
Aims/hypothesis Islets have complex heterogeneity and subpopulations. Cell surface
markers representing alpha, beta and delta cell subpopulations are urgently needed for …
markers representing alpha, beta and delta cell subpopulations are urgently needed for …
Spatial Proteomics towards cellular Resolution
Introduction Spatial biology is an emerging interdisciplinary field facilitating biological
discoveries through the use of spatial omics technologies. Recent advancements in spatial …
discoveries through the use of spatial omics technologies. Recent advancements in spatial …
The 37TrillionCells initiative for improving global healthcare via cell-based interception and precision medicine: focus on neurodegenerative diseases
One of the main burdens in the treatment of diseases is imputable to the delay between the
appearance of molecular dysfunctions in the first affected disease cells and their presence in …
appearance of molecular dysfunctions in the first affected disease cells and their presence in …
Solid-phase alkylation: a low-loss and anti-interference sample preparation strategy for low-input proteome profiling
Solid-phase alkylation: a low-loss and anti-interference sample preparation strategy for low-input
proteome profiling Solid-phase alkylation: a low-loss and anti-interference sample preparation …
proteome profiling Solid-phase alkylation: a low-loss and anti-interference sample preparation …
基于质谱的单细胞蛋白质组学技术的发展及应用.
顾蕾， 张誉露， 唐尚睿， 于浩月… - Biotechnology Bulletin, 2024 - search.ebscohost.com
单细胞多组学技术为生命科学和医学注入新的活力, 能够从更微观的细胞尺度,
更高维的时空角度, 更交叉的组学视野来探索生命的未知, 拓展医学的边界 …
更高维的时空角度, 更交叉的组学视野来探索生命的未知, 拓展医学的边界 …