Carnitine Palmitoyl-Transferase1A (CPT1A) is the rate-limiting enzyme in the fatty acid β-
oxidation, and its deficiency or abnormal regulation can result in diseases like metabolic …

Cancer metabolism has received a substantial amount of interest over the past decade. The
advances in analytical tools have, along with the rapid progress of cancer genomics …

Obesity and related metabolic diseases are becoming worldwide epidemics that lead to
increased death rates and heavy health care costs. Effective treatment options have not …

Cancer therapy has long relied on the rapid proliferation of tumour cells for effective
treatment. However, the lack of specificity in this approach often leads to undesirable side …

Dysregulation of cancer cell metabolism contributes to abnormal cell growth, the biological
end point of cancer. We review here numerous affected oncogenes and metabolic pathways …

Background Enhanced macromolecule biosynthesis is integral to growth and proliferation of
cancer cells. Lipid biosynthesis has been predicted to be an essential process in cancer …

Significance: Current lifestyles with high-energy diets and little exercise are triggering an
alarming growth in obesity. Excess of adiposity is leading to severe increases in associated …

Insulin sensitizers like metformin generally act through pathways triggered by adenosine
monophosphate‐activated protein kinase. Carnitine palmitoyltransferase 1 (CPT1) controls …

Abstract Carnitine palmitoyltransferase 1 (CPT1) C was the last member of the CPT1 family
of genes to be discovered. CPT1A and CPT1B were identified as the gate-keeper enzymes …

Cellular energy metabolism is one of the main processes affected during the transition from
normal to cancer cells, and it is a crucial determinant of cell proliferation or cell death. As a …