[HTML][HTML] Physiology of the endometrium and regulation of menstruation

HOD Critchley, JA Maybin… - Physiological …, 2020‏ - journals.physiology.org
The physiological functions of the uterine endometrium (uterine lining) are preparation for
implantation, maintenance of pregnancy if implantation occurs, and menstruation in the …

Uterine bleeding: how understanding endometrial physiology underpins menstrual health

V Jain, RR Chodankar, JA Maybin… - Nature reviews …, 2022‏ - nature.com
Menstruation is a physiological process that is typically uncomplicated. However, up to one
third of women globally will be affected by abnormal uterine bleeding (AUB) at some point in …

[HTML][HTML] Physiology, menstrual cycle

DK Thiyagarajan, H Basit, R Jeanmonod - StatPearls [Internet], 2024‏ - ncbi.nlm.nih.gov
The female reproductive system, unlike the male, undergoes regular cyclic changes known
as the menstrual cycle, which serves as the body's periodic preparation for ovulation and …

Analysis of serum and endometrial progesterone in determining endometrial receptivity

E Labarta, P Sebastian-Leon… - Human …, 2021‏ - academic.oup.com
STUDY QUESTION Is there a relationship between serum and endometrial progesterone
(P4) levels, including P4 and metabolites (oestrone, oestradiol and 17α …

Scaffold-free endometrial organoids respond to excess androgens associated with polycystic ovarian syndrome

T Wiwatpanit, AR Murphy, Z Lu… - The Journal of …, 2020‏ - academic.oup.com
Context Polycystic ovary syndrome (PCOS) is a prevalent disorder in reproductive aged
women associated with a number of endocrine and metabolic complications, including …

Breakthrough bleeding in transgender and gender diverse adolescents and young adults on long-term testosterone

F Grimstad, J Kremen, J Shim, BM Charlton… - Journal of Pediatric and …, 2021‏ - Elsevier
ABSTRACT Study Objective Amenorrhea is a goal of many transgender and gender diverse
adolescent and young adult (TGD AYA) patients on testosterone gender-affirming hormone …

Androgens, oestrogens and endometrium: a fine balance between perfection and pathology

DA Gibson, I Simitsidellis, F Collins… - Journal of …, 2020‏ - joe.bioscientifica.com
The endometrium is a complex multicellular tissue that is exquisitely sensitive to the actions
of sex steroids synthesised in the ovary (endocrine system). Recent studies have highlighted …

[HTML][HTML] The crowded crosstalk between cancer cells and stromal microenvironment in gynecological malignancies: biological pathways and therapeutic implication

R De Nola, A Menga, A Castegna, V Loizzi… - International journal of …, 2019‏ - mdpi.com
The tumor microenvironment plays a pillar role in the progression and the distance
dissemination of cancer cells in the main malignancies affecting women—epithelial ovarian …

A relational database to identify differentially expressed genes in the endometrium and endometriosis lesions

M Gabriel, V Fey, T Heinosalo, P Adhikari, K Rytkönen… - Scientific data, 2020‏ - nature.com
Endometriosis is a common inflammatory estrogen-dependent gynecological disorder,
associated with pelvic pain and reduced fertility in women. Several aspects of this disorder …

Genetically predicted serum testosterone and risk of gynecological disorders: a Mendelian randomization study

B Zhao, Z Wang, D Liu, S Zhang - Frontiers in Endocrinology, 2023‏ - frontiersin.org
Background Testosterone plays a key role in women, but the associations of serum
testosterone level with gynecological disorders risk are inconclusive in observational …