Heat shock proteins regulatory role in neurodevelopment

DJ Miller, PE Fort - Frontiers in neuroscience, 2018 - frontiersin.org
Heat shock proteins (Hsps) are a large family of molecular chaperones that are well-known
for their roles in protein maturation, re-folding and degradation. While some Hsps are …

Vitreous and vision degrading myodesopsia

J Sebag - Progress in Retinal and Eye Research, 2020 - Elsevier
Macromolecules comprise only 2% of vitreous, yet are responsible for its gel state,
transparency, and physiologic function (s) within the eye. Myopia and aging alter collagen …

Molecular genetics of congenital cataracts

J Li, X Chen, Y Yan, K Yao - Experimental Eye Research, 2020 - Elsevier
Congenital cataracts, the most common cause of visual impairment and blindness in
children worldwide, have diverse etiologies. According to statistics analysis, about one …

[HTML][HTML] Generation of lens progenitor cells and lentoid bodies from pluripotent stem cells: novel tools for human lens development and ocular disease etiology

A Cvekl, MJ Camerino - Cells, 2022 - mdpi.com
In vitro differentiation of human pluripotent stem cells (hPSCs) into specialized tissues and
organs represents a powerful approach to gain insight into those cellular and molecular …

Regulation of the rhythmic diversity of daily photoreceptor outer segment phagocytosis in vivo

AL Moran, JD Fehilly, D Floss Jones… - The FASEB …, 2022 - Wiley Online Library
Outer segment phagocytosis (OSP) is a highly‐regulated, biological process wherein
photoreceptor outer segment (OS) tips are cyclically phagocytosed by the adjacent retinal …

Neonatal and juvenile ocular development in göttingen minipigs and domestic pigs: a histomorphological and immunohistochemical study

V Vrolyk, MJ Desmarais, D Lambert… - Veterinary …, 2020 - journals.sagepub.com
Pigs are considered one of the relevant animal models for ocular research as they share
several histological and anatomical similarities with the human eye. With the increasing …

Bidirectional analysis of Cryba4-Crybb1 nascent transcription and nuclear accumulation of Crybb3 mRNAs in lens fibers

S Limi, Y Zhao, P Guo, M Lopez-Jones… - … & Visual Science, 2019 - iovs.arvojournals.org
Purpose: Crystallin gene expression during lens fiber cell differentiation is tightly spatially
and temporally regulated. A significant fraction of mammalian genes is transcribed from …

Sub-nanometre map** of the aquaporin–water interface using multifrequency atomic force microscopy

M Ricci, RA Quinlan, K Voïtchovsky - Soft Matter, 2017 - pubs.rsc.org
Aquaporins are integral membrane proteins that regulate the transport of water and small
molecules in and out of the cell. In eye lens tissue, circulation of water, ions and metabolites …

Immunohistochemical Detection of Encephalitozoon cuniculi in Ocular Structures of Immunocompetent Rabbits

E Jeklová, L Levá, V Kummer, V Jekl, M Faldyna - Animals, 2019 - mdpi.com
Simple Summary Encephalitozoonosis is a common infectious disease widely spread
among rabbits. Its causative agent, Encephalitozoon cuniculi, is considered to be …

[HTML][HTML] Involvement of anoikis in dissociated optic nerve fiber layer appearance

T Ikeda, K Nakamura, T Sato, T Kida, H Oku - International Journal of …, 2021 - mdpi.com
Dissociated optic nerve fiber layer (DONFL) appearance is characterized by dimpling of the
fundus when observed after vitrectomy with the internal limiting membrane (ILM) peeling in …